In professional American football, the Pro Bowl is the all-star game of the National Football League (NFL). Since the merger with the rival American Football League (AFL) in 1970, it has been officially called the AFC–NFC Pro Bowl, matching the top players in the American Football Conference (AFC) against those in the National Football Conference (NFC).

Unlike most other sports leagues, which hold their all-star games during (roughly) the halfway point of their respective regular seasons, the Pro Bowl is played at the end of the NFL season. The NFL's all-star game draws bigger television ratings than all other major sports all-star games. The 2012 Pro Bowl drew 13.5 million viewers. . However, the biggest concern of teams is to avoid injuries to the star players. The Associated Press wrote that players in the 2012 game were "hitting each other as though they were having a pillow fight."

The first "Pro All-Star Game," featuring the all-stars of the 1938 season (as well as three players from the Hollywood Stars and Los Angeles Bulldogs, who were not members of the league), was played on January 15, 1939 at Los Angeles's Wrigley Field. The NFL All-Star Game was played again in Los Angeles in 1940 and then in New York and Philadelphia in 1941 and 1942 respectively. Although originally planned as an annual contest, the all-star game was discontinued after 1942 because of travel restrictions put in place during World War II. During the first five all-star games, an all-star team would face that year's league champion. The league champion won the first four games before the all-stars were victorious in the final game of this early series.

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