Takeshi Yamamoto (山本 武, Yamamoto Takeshi^?) is a fictional character in the Reborn! manga and anime series created by Akira Amano. Portrayed as one of the protagonist's first friends, Takeshi Yamamoto is introduced as a 14-year-old starting pitcher for his school's baseball team. Apart from the manga and anime, Yamamoto has also appeared in other media from the Reborn! franchise including video games.

Yamamoto's character has been well-received by readers since his introduction, ranking as one of the most popular characters in every official Shonen Jump poll of the series. Publications for manga, anime and other media have commented on his character. Merchandise based on his appearance has also been released including key chains and action figures.

Rarely seen angry, Yamamoto has a warm and friendly personality and is a peacemaker that occurs between his comrades. He is popular among his classmates, especially girls and loves to play baseball (In the manga) to the point of attempting suicide when he is unable to play. Because of baseball, Yamamoto focuses on protecting his energy and his body in baseball and battle. However, as the series progresses, he decides not to focus on protecting his body so he can protect his friends and family using all of his strength. He does not like to lose and is ridden with guilt and regret upon defeat.

Ryohei Sasagawa (笹川 了平, Sasagawa Ryōhei^?) is a fictional character in the anime and manga series Reborn! created by Akira Amano. He has also appeared in other media from the Reborn! franchise including video games and light novels. Ryohei is portrayed as one of the series' protagonists, and is introduced as the energetic member of the boxing club at Namimori Middle School. He would often attempt to get the main character, Tsuna Sawada, to join his club, and in response, Tsuna's home tutor, Reborn, attempts to get him to join Tsuna's personal Mafia family. His role is initially minimal, usually only having brief appearances since his introduction. Becoming the Vongola Family's Sun Guardian is what leads to his first significant and recurring involvement in the story.

Ryohei is the older brother of the Tsuna's love interest, Kyoko. He is a boxing-obsessed student who often prefers to fight his opponents head on and sees any disadvantage as a chance to improve his fighting skills. He is always hiding the truth of what he is doing from Kyoko due to an incident that happened when they were still in primary school: some high school students who did not like Ryohei used Kyoko to lure him into a trap, which resulted in the scar on his left temple. Though Kyoko feels responsible, he was not dissuaded and continued to fight.

Suguru Inoue (優 井上, Inoue Suguru^?, born December 4, 1981 in Kanagawa, Japan) is a Japanese voice actor.

(lead roles are in bold)

Hayato Gokudera (獄寺 隼人, Gokudera Hayato^?) is a fictional character in the anime and manga series Reborn! created by Akira Amano. Portrayed as one of the protagonist's first friends, Hayato Gokudera is introduced as a 14-year-old bad boy born in Italy. After the protagonist Tsuna Sawada prevents him from dying due to his own explosives, he joins Tsuna's Vongola Mafia family. Apart from the manga and anime, Gokudera has also appeared in other media from the Reborn! franchise including video games.

When he was younger, he was a talented pianist. However, he soon decided to join the Mafia after his mother's death. His father is also reportedly a member of a Mafia family. Unfortunately, no one wanted to accept him into their family; the fact that he was an oriental half-breed lessened his chances of finding a Mafia family to take him in. To become stronger, he sought advice from Dr. Shamal, who, at the time, was working for his family. Gokudera seemed to have looked up to Shamal who taught him how to use dynamite.