Drury Hotels, LLC, or Drury Hotels is a Cape Girardeau, Missouri based corporation that operates over 130 hotels in a 20 state area.The company employs approximately 4,000 people.^[when?]

The company traces its origins back to the 1940s when Lambert Drury began a plastering business.^{[clarification needed]} In 1973, the family opened its first hotel in Sikeston, Missouri. The hotel initially charged around 25% below the base tariff offered by other hotels in the area.^{[citation needed]}

In addition to the Drury Inn line of hotels, the company also operates a Pear Tree Inn line of hotels. Many Pear Tree Inns are first generation Drury Inns, when the company replaced the older buildings with a new Drury Inn^[when?]. If the company had not torn down the old building they often rebranded the old building as a Pear Tree Inn. An example of this is in Overland Park, Kansas: the original Drury Inn became a Pear Tree Inn when another Drury Inn opened at the same address.^{[clarification needed]}

Drury Hotels served as a sponsor for the 2007, 2008 and 2009 Tour of Missouri.