In human anatomy, the wrist is variously defined as 1) the carpus or carpal bones, the complex of eight bones forming the proximal skeletal segment of the hand; (2) the wrist joint or radiocarpal joint, the joint between the radius and the carpus; and (3) the anatomical region surrounding the carpus including the distal parts of the bones of the forearm and the proximal parts of the metacarpus or five metacarpal bones and the series of joints between these bones, thus referred to as wrist joints. This region also includes the carpal tunnel, the anatomical snuff box, the flexor retinaculum, and the extensor retinaculum.

As a consequence of these various definitions, fractures to the carpal bones are referred to as carpal fractures, while fractures such as distal radius fracture are considered fractures to the wrist.

The English word "wrist" is etymologically derived from the ancient German word wristiz from which are derived modern German rist ("instep", "wrist") and modern Swedish vrist ("instep", "ankle"). The base writh- and its variants are associated with Old English words "wreath", "wrest", and "writhe". The wr- sound of this base seems originally to have been symbolic of the action of twisting.