- published: 22 Nov 2014
- views: 8918
Choline is a water-soluble nutrient. It is usually grouped within the B-complex vitamins. Choline generally refers to the various quaternary ammonium salts containing the N,N,N-trimethylethanolammonium cation. (X− on the right denotes an undefined counteranion.)
The cation appears in the head groups of phosphatidylcholine and sphingomyelin, two classes of phospholipid that are abundant in cell membranes. Choline is the precursor molecule for the neurotransmitter acetylcholine, which is involved in many functions including memory and muscle control.
Some animals must consume choline through their diet to remain healthy. To humans, choline is not an essential nutrient unless the diet is also devoid of methionine and folate. It is used in the synthesis of components in cell membranes. The 2005 National Health and Nutrition Examination Survey stated that only 2% of postmenopausal women consume the recommended intake for choline.
Choline was first isolated by Adolph Strecker from pig and ox bile (Greek: χολή, chole) in 1862. When it was first chemically synthesized by Oscar Liebreich in 1865, it was known as neurine until 1898 when it was shown to be chemically identical to choline. In 1998, choline was classified as an essential nutrient by the Food and Nutrition Board of the Institute of Medicine (USA).
Got your invitation
Bless your heart, you're good to call
Another night on the town
With everyone around
Doesn't seem that fun at all
Since we're very important
People, we can skip the line
I can do you one better
We'll skip it all together
And the pleasure will be mine
But I'll try to make it
Hope I can make it
Try to make it now
Hope I can make it
You said you would meet me
If I'm halfway interested
I'd be upset if you waited
Frankly, stunned if I made it
I insist you go ahead
I mean to be gracious
But I feel put on the spot
If I'm not acting excited
That I was invited
It's because I'm kinda not
But I'll try to make
Hope I can make it
Try to make it now
Hope I can make it
Notice I'm under
House arrest that's self-imposed
Started to wonder
What we do behind doors when they're closed
Try to make it now
Hope you can make it
Sent an invitation
I left it stuck up on your door
Cause when I need you, you're there
If you come over, I swear
I won't be stuck up anymore
I've come to my senses
I was blind, but now I see
Down go my defenses
I'm begging you to spend your time with me
Try to make it now
Hope you can make it
Try to make it now
Hope you can make it
Try to make it now
Hope you can make it
Try to make it now
Hope you can make it