DuBois /ˈduːbɔɪz/ DOO-boys is a city in Clearfield County, Pennsylvania, United States, 100 miles (160 km) northeast of Pittsburgh. The population was 7,794 at the 2010 census. It is the principal city in the DuBois, PA Micropolitan Statistical Area. DuBois is also one of two principal cities, the other being State College, that make up the larger State College-DuBois, PA Combined Statistical Area.
Settled in 1812 and platted in 1872, DuBois was incorporated as a borough in 1881 and as a city in 1914.
The town was founded by John Rumbarger, for whom the town was originally named. The Rumbarger Cemetery is all that survives of this original settlement. The town was later renamed for local lumber magnate John DuBois, who came from a longstanding American family of French Huguenot descent. In 1938, his nephew, John E. DuBois, donated the family mansion and estate as a permanent home for the DuBois Campus of Penn State University. While DuBois was founded as a lumber town, the mining of bituminous coal quickly became the chief industry in DuBois.
This is a list of minor planets with numbers 206,001–207,000. To navigate the full list see List of minor planets § Main index.
Breath of Fire II (Japanese: ブレス オブ ファイアII 使命の子, Hepburn: Buresu obu Faia Tsū: Shimei no Ko, Breath of Fire II: The Destined Child) is a role-playing video game developed and published by Capcom. First released in 1994, the game was licensed to Laguna for European release in 1996. It is the second entry in the Breath of Fire series. It was later ported to Game Boy Advance and re-released worldwide. The game has been rated by the ESRB for release on Wii's Virtual Console and was released in North America on August 27, 2007. Nintendo of Europe's website mistakenly announced it for release on July 27, 2007, but it was in fact released two weeks later, on August 10, 2007.
Unlike later installments in the series, Breath of Fire II is a direct sequel to Breath of Fire. Set 500 years after the original game, the story centers on an orphan named Ryu Bateson, whose family vanished mysteriously long ago. After his friend is falsely accused of a crime, Ryu embarks on a journey to clear his name.
Jean Raphael Vanderlei Moreira or simply Jean (born 24 June 1986 in Campo Grande), is a Brazilian footballer who plays for Fluminense. Mainly a defensive midfielder, he can also play as a right defender.
Made professional debut for São Paulo in a 1-2 away defeat to Santos in the Campeonato Brasileiro on 17 July 2005.
On 13 November 2012 Jean was called up, by Mano Menezes, for Brazil that will play Superclásico de las Américas, making, then, his début for Seleção.
Games for Brazilian team
Brazil
Jean /ˈdʒiːn/ is a common female given name in English-speaking countries. It is the Scottish form of Jane (and is sometimes pronounced that way). It is sometimes spelt Jeaine. It is the equivalent of Johanna, Joanna, Joanne, Jeanne, Jana, and Joan.
Famous people with the given name Jean:
DNA polymerase delta is an enzyme complex found in eukaryotes that is involved in DNA replication and repair. The DNA polymerase delta complex consists of 4 subunits: POLD1, POLD2, POLD3, and POLD4. DNA Pol δ is the enzyme used primarily for leading and lagging strand synthesis. It exhibits increased processivity when interacting with the proliferating cell nuclear antigen (PCNA). As well, the multisubunit protein replication factor C, through its role as the clamp loader for PCNA (which involves catalysing the loading of PCNA on to DNA) is important for DNA Pol δ function.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
The DNA polymerases are enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA. These enzymes are essential to DNA replication and usually work in pairs to create two identical DNA strands from a single original DNA molecule. During this process, DNA polymerase “reads” the existing DNA strands to create two new strands that match the existing ones.
Every time a cell divides, DNA polymerase is required to help duplicate the cell’s DNA, so that a copy of the original DNA molecule can be passed to each of the daughter cells. In this way, genetic information is transmitted from generation to generation.
Before replication can take place, an enzyme called helicase unwinds the DNA molecule from its tightly woven form. This opens up or “unzips” the double-stranded DNA to give two single strands of DNA that can be used as templates for replication.
In 1956, Arthur Kornberg and colleagues discovered the enzyme DNA polymerase I, also known as Pol I, in Escherichia coli. They described the DNA replication process by which DNA polymerase copies the base sequence of a template DNA strand. Subsequently, in 1959, Kornberg was awarded the Nobel Prize in Physiology or Medicine for this work.DNA polymerase II was also discovered by Kornberg and Malcolm E. Gefter in 1970 while further elucidating the role of Pol I in E. coli DNA replication.