Lisboa Region (Portuguese: Região de Lisboa) is one of the seven NUTS II designated regions of Portugal, that includes two NUTS III subregions: Greater Lisbon and Peninsula of Setúbal. The region covers an area of 2710.24 km² (the smallest region on mainland Portugal) and includes a population of 2,815,851 inhabitants according to the 2011 census (a density of 1039 inhabitants per kilometer square of territory.

Prior to 2002 the area was included within the NUTS II region of Lisbon and Tagus Valley (that also included three other subregions).

"Despite the territorial configuration for statistical purposes (National Statistical System in Portugal), in force since 2007, matching the NUTS II the Lisbon, Region Greater Lisbon (AML) - composed only NUTSIII Greater Lisbon and Setúbal Peninsula - the area of intervention of the CCDRLVT - Steering Committee and Regional Development, abbreviated to CCDR - (the Lisbon and the Tagus Valley), continues to be composed of 5 NUTSIII (Sub-regions: Greater Lisbon, Setúbal Peninsula, Middle Tagus, and Lezíria West Coast).