Patricia Reyes Spíndola (born Patricia Verónica Núñez Reyes Spíndola on 11 July 1953 in Oaxaca, Mexico) is a Mexican actress, director and producer.
Spíndola studied to become an actress in several ateliers in Mexico and London. She made her début in the movies in 1972, with El señor de Osanto, and two years later she started working in the Teatro Fru Fru.
As an actress, she has worked with directors like Nancy Cárdenas or Arturo Ripstein.
She has also worked in Mexican telenovelas. She won the Ariel prize for her roles in Los motivos de Luz and La reina de la noche.
She has an acting school she runs with her sister, Marta Reyes Spíndola, in the Colonia Juárez neighborhood of Mexico City called M & M Studio, where she also teaches.
She also guest starred in 4 episodes of AMC's Fear the Walking Dead as Griselda Salazar in 2015.