Parasites'winner-takes-all mechanism to evade immune defenses (University of Dundee)

Edit Public Technologies 27 May 2016
(Source. University of Dundee). Published OnFri 27 May 2016by Roddy Isles. A genetic game of `winner takes all' that sustains the parasitic infections which cause sleeping sickness in humans and nagana in cattle - devastating diseases particularly in rural areas of Africa - has been identified in a research breakthrough led by the University of Dundee ... VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes....

Nearly 50 million euros of ERC grants for EPFL, despites obstacles (EPFL - École Polytechnique Fédérale de Lausanne)

Edit Public Technologies 27 May 2016
(Source. EPFL - École Polytechnique Fédérale de Lausanne). 27.05.16- EPFL fared well in the competition for European Research Council (ERC) grants in 2014 and 2015 within the Horizon 2020 framework, with 11 researchers winning an Advanced Grant ... We will use a large genomic interval in mouse chromosome 2 containing the HoxD cluster as a paradigm, as it is covered by a large allelic series re-organizing the topology of this interval ... 1 ... 2....

L'EPFL a décroché 50 millions d'euros de «grants» malgré les écueils (EPFL - École Polytechnique Fédérale de Lausanne)

Edit Public Technologies 27 May 2016
(Source. EPFL - École Polytechnique Fédérale de Lausanne). 27.05.16- La course aux «ERC Grants» a souri à l'EPFL ces deux dernières années. Entre 2014 et 2015, onze chercheurs ont reçu un «Advanced grant» dans le cadre du programme «Horizon 2020» ... We will use a large genomic interval in mouse chromosome 2 containing the HoxD cluster as a paradigm, as it is covered by a large allelic series re-organizing the topology of this interval ... 1 ... 2....

Editing Genomes to Record Cellular Histories

Edit The Scientist 26 May 2016
Mutating a specific synthetic DNA element in engineered zebrafish embryos has enabled researchers to irreversibly tag cells and their progeny during development, according to a report published in Science today (May 26) ... Indeed, in most organs, fewer than 25 alleles (mutated versions of the array) gave rise to more than 90 percent of the cells. As an extreme example, just five alleles defined more than 98 percent of cells in the blood....

New evidence on molecular mechanisms involved in psoriasis outset (Universitat de Barcelona)

Edit Public Technologies 25 May 2016
(Source. Universitat de Barcelona). The researchers (left to right) Ester Ruiz, Laura Sòria, Lluís Santamaria, Ester Gil and David Cabrerizo. 24/05/2016. Recerca ... Guttate psoriasis origins ... Although the causes of this disease are unknown, it usually happens after a tonsillitis infection, which seems to provoke an excessive autoimmune reaction ... In addition, this reaction happens especially in samples that have HLACw6 allele ... E. Ruiz-Romeu, M....

Olfactory receptor selection [Physics]>

Edit PNAS 24 May 2016
Multiple-objective optimization is common in biological systems. In the mammalian olfactory system, each sensory neuron stochastically expresses only one out of up to thousands of olfactory receptor (OR) gene alleles; at the organism level, the types of expressed ORs need to be maximized. Existing models focus only on monoallele activation,... ....

BRIEF-Rosetta Genomics announces receipt of conditional approval

Edit Reuters 23 May 2016
* Receipt of conditional approval from new york state department of health for company's allele-specific pcr based assays Source text for Eikon. Further company coverage. (Bengaluru Newsroom.... ....

Rosetta Genomics Receives Approval from New York State for Four PCR-Based Assays

Edit Business Wire 23 May 2016
PHILADELPHIA & REHOVOT, Israel--(BUSINESS WIRE)--Rosetta Genomics Ltd. (NASDAQ.ROSG), a leading developer and provider of microRNA-based and other molecular diagnostic testing services, announces receipt of conditional approval from the New York State Department of Health (NYSDOH) for the Company’s allele-specific PCR (CAST PCR)-based assays to test for BRAF, EGFR, KRAS and NRAS mutations in lung, colon and melanoma cancers ... ....

Rosetta Genomics Receives Approval from New York State for Four PCR-based Assays (Rosetta Genomics Ltd)

Edit Public Technologies 23 May 2016
(Source. Rosetta Genomics Ltd) ccde9971-d3a8-4919-bc8c-ee8ffee2b283.pdf ... (NASDAQ. ROSG), a leading developer and provider of microRNA-based and other molecular diagnostic testing services, announces receipt of conditional approval from the New York State Department of Health (NYSDOH) for the Company's allele-specific PCR (CAST PCR)-based assays to test for BRAF, EGFR, KRAS and NRAS mutations in lung, colon and melanoma cancers ... Berlin....

These genes may increases your chances of a second date!

Edit DNA India 22 May 2016
--> ... ALSO READ ... ALSO READ ... When it came to -1438 A/G, men who carried its G-allele variation were rated as more desirable potential mates and were more likely to receive second date offers. In contrast, women who carried this G-allele were more likely to be given the cold shoulder by men. With A118G, women with the G-allele enjoyed greater speed-dating success ... Men with this G-allele were less desirable to their speed-dating partners ... ....

Gender-stereotypic genes may boost chances of second date!

Edit Deccan Chronicle 21 May 2016
Los Angeles ... sensitivity/submissiveness in women ... When it came to -1438 A/G, men who carried its G-allele variation were rated as more desirable potential mates and were more likely to receive second date offers. In contrast, women who carried this G-allele were more likely to be given the cold shoulder by men. With A118G, women with the G-allele enjoyed greater ... Men with this G-allele were less desirable to their speed-dating partners ... ....

‘A headlong sprint into an abyss’

Edit The Washington Post 20 May 2016
Through a very good source I obtained a document given to college students to prepare them for a midterm test in an introductory biology class, and it included a list of technical terms, like “allele” and “codon” and “meiosis” and “introns” and “recombination pleiotropy” and “plesiomorphic traits” and various other genetic and biological and evolutionary […]> ... ....

How science can make bones and ashes speak

Edit Indian Express 19 May 2016
But no results could be determined for eight other markers since what are known as “mixed alleles” were present. How these “mixed alleles” ended up in charred bits of human tissue, each of which, obviously, should have come from just one person, is completely unexplained in the report. An allele is one of a pair of genes ... Each allele has a specific function, like determining blood type, or eye colour....
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