George Walker Bush (born July 6, 1946) is an American politician and businessman who was the 43rd President of the United States from 2001 to 2009 and the 46th Governor of Texas from 1995 to 2000. The eldest son of Barbara Bush and George H. W. Bush, he was born in New Haven, Connecticut. After graduating from Yale University in 1968 and Harvard Business School in 1975, Bush worked in oil businesses. He married Laura Welch in 1977 and ran unsuccessfully for the House of Representatives shortly thereafter. He later co-owned the Texas Rangers baseball team before defeating Ann Richards in the 1994 Texas gubernatorial election. In a close and controversial election, Bush was elected President in 2000 as the Republican candidate, defeating Vice President Al Gore in the Electoral College. Bush is the second American president to have been the son of a former president. He is also the brother of Jeb Bush, former Governor of Florida.

Terrorist attacks occurred eight months into Bush's first term as president on September 11, 2001. In response, Bush announced the War on Terror, an international military campaign which included the war in Afghanistan launched in 2001 and the war in Iraq launched in 2003. In addition to national security issues, Bush promoted policies on the economy, health care, education, and social security reform. He signed into law broad tax cuts, the PATRIOT Act, the No Child Left Behind Act, the Partial-Birth Abortion Ban Act, and Medicare prescription drug benefits for seniors. His tenure saw national debates on immigration, Social Security, electronic surveillance, and enhanced interrogation techniques. His administration also withdrew the U.S. from a some international treaty processes, including the Kyoto Protocol on global warming.

William Jefferson "Bill" Clinton (born William Jefferson Blythe III; August 19, 1946) is an American politician who served as the 42nd President of the United States from 1993 to 2001. Inaugurated at age 46, he was the third-youngest president. He took office at the end of the Cold War, and was the first president of the baby boomer generation. Clinton has been described as a New Democrat. Many of his policies have been attributed to a centrist Third Way philosophy of governance.

Born and raised in Arkansas, Clinton became both a student leader and a skilled musician. He is an alumnus of Georgetown University where he was Phi Beta Kappa and earned a Rhodes Scholarship to attend the University of Oxford. He is married to Hillary Rodham Clinton, who has served as the United States Secretary of State since 2009 and was a Senator from New York from 2001 to 2009. Both Clintons received law degrees from Yale Law School, where they met and began dating. As Governor of Arkansas, Clinton overhauled the state's education system, and served as Chair of the National Governors Association.

Nancy Davis Reagan (born Anne Frances Robbins; July 6, 1921) is the widow of former United States President Ronald Reagan and was First Lady of the United States from 1981 to 1989.

Nancy was born in New York City; her parents divorced soon after her birth and she grew up in Maryland, living with an aunt and uncle while her mother pursued acting jobs. As Nancy Davis, she was an actress in Hollywood in the 1940s and 1950s, starring in films such as Donovan's Brain, Night into Morning, and Hellcats of the Navy. In 1952 she married Ronald Reagan, who was then president of the Screen Actors Guild, and they had two children. Nancy was the First Lady of California when her husband was Governor from 1967 to 1975. In that capacity, she began work with the Foster Grandparents Program.

Nancy Reagan became First Lady of the United States in January 1981 following her husband's election. She was criticized early in his first term largely due to her decision to replace the White House china, despite it being paid for by private donations. Nancy restored a Kennedy-esque glamor to the White House following years of lax formality, and her interest in high-end fashion garnered much attention, as well as criticism. She championed recreational drug prevention causes by founding the "Just Say No" drug awareness campaign, which was considered her major initiative as first lady. Always protective of her husband, more controversy ensued when it was revealed in 1988 that she had consulted an astrologer to assist in planning the president's schedule after the 1981 assassination attempt on her husband. She had a strong influence on her husband and played a role in a few of his personnel and diplomatic decisions.