Latest News for: trna

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Dynamic changes in tRNA modifications and abundance during T cell activation [Cell Biology]

PNAS 12 Oct 2021
The tRNA pool determines the efficiency, throughput, and accuracy of translation.
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The Clp1 R140H mutation alters tRNA metabolism and mRNA 3' processing in mouse models of ...

PNAS 21 Sep 2021
CLP1 is associated with the transfer RNA (tRNA) splicing endonuclease ...
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aTyr Pharma Announces Grant of U.S. Patent for Use of Histidyl-tRNA Synthetase Fc Fusion Proteins ...

Nasdaq Globe Newswire 30 Jul 2021
Patent and Trademark Office (USPTO) has granted a patent covering methods for the use of histidyl-tRNA synthetase Fc fusion ...
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aTyr Pharma Announces Grant of U.S. Patent for Use of Histidyl-tRNA Synthetase Fc Fusion Proteins for Reducing Inflammatory Response in the Lung (aTyr Pharma Inc)

Public Technologies 29 Jul 2021
Patent and Trademark Office (USPTO) has granted a patent covering methods for the use of histidyl-tRNA synthetase Fc fusion proteins for reducing inflammatory response in the lung ... 11,072,787 entitled, 'Histidyl-tRNA synthetase-FC conjugates,' covers the use of the company's lead ...
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Birds take tRNA efficiency to new heights

Phys Dot Org 14 Apr 2021
According to Kutter, "While ongoing genome assembly efforts had shown that bird genomes have a smaller genome size, we were not expecting that this would also affect tRNA genes, since tRNA gene redundancy ensures that enough tRNA molecules are transcribed for efficient mRNA translation." ... The birth of a bacterial tRNA gene.
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Measuring the tRNA world

Science Daily 26 Feb 2021
... physiology, but measuring the amount of each tRNA in cells has been limited by technical challenges.
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aTyr Pharma Announces New tRNA Synthetase Discovery Programs

Nasdaq Globe Newswire 11 Feb 2021
Advancement of selected AARS and DARS fragments primarily targeting cancer ... .
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aTyr Pharma Announces New tRNA Synthetase Discovery Programs (aTyr Pharma Inc)

Public Technologies 11 Feb 2021
LIFE), a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways, today announced that it has initiated two new discovery programs from its tRNA synthetase platform ... and signaling pathways of tRNA synthetases.
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aTyr Pharma to Present Poster Highlighting Research Approach for Identifying Receptor Targets for Extracellular tRNA Synthetases (aTyr Pharma Inc)

Public Technologies 22 Jan 2021
Research approach led to the identification of target receptors for two tRNA synthetases and further validates company's biology platform ... The poster describes a mass spectrometry proteomics-based approach to identify target receptors for two distinct extracellular tRNA synthetase fragments.
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tRNA fragments are involved in post-stroke immune reactions

Science Daily 11 Dec 2020
Now, a team of researchers has shown that tRNA fragments play a role in this immune ...
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