- published: 04 May 2016
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Alcohol intoxication (also known as drunkenness or inebriation) is a physiological state that occurs when a person has a high level of ethanol (alcohol) in his or her blood.
Common symptoms of alcohol intoxication include slurred speech, euphoria, impaired balance, loss of muscle coordination (ataxia), flushed face, vomiting, reddened eyes, reduced inhibition, and erratic behavior. In severe cases, it can cause coma or death.
Toxicologists use the term “alcohol intoxication” to discriminate between alcohol and other toxins.
Acute alcohol intoxication results from a very high level of alcohol in the blood. This term is used by health care providers, often in emergencies.
Alcohol is metabolized by a normal liver at the rate of about one ounce (one "highball", a normal beer, a regular sized glass of wine) every 90 minutes. An "abnormal" liver with conditions such as hepatitis, cirrhosis, gall bladder disease, and cancer will have a slower rate of metabolism.
Ethanol is metabolised to acetaldehyde by alcohol dehydrogenase (ADH), which is found in many tissues, including the gastric mucosa. Acetaldehyde is metabolised to acetate by acetaldehyde dehydrogenase (ALDH), which is predominantly found in liver mitochondria. Acetate is used by the muscle cells to produce acetyl-CoA using the enzyme acetyl-CoA synthetase, and the acetyl-CoA is then used in the citric acid cycle. It takes roughly 90 minutes for a healthy liver to metabolize a single ounce, approximately one hour per standard unit.
Donald John Trump, Sr. (born June 14, 1946) is an American business magnate, television personality and author. He is the chairman and president of The Trump Organization and the founder of Trump Entertainment Resorts. Trump's extravagant lifestyle, outspoken manner and role on the NBC reality show The Apprentice have made him a well-known celebrity who was No. 17 on the 2011 Forbes Celebrity 100 list. He is well-known as a real-estate developer who amassed vast hotel, casino, and other real-estate properties, in the New York City area and around the world.
Trump is the son of Fred Trump, a wealthy New York City real-estate developer. He worked for his father's firm, Elizabeth Trump & Son, while attending the Wharton School of the University of Pennsylvania, and in 1968 officially joined the company. He was given control of the company in 1971 and renamed it The Trump Organization.
In 2010, Trump expressed an interest in becoming a candidate for President of the United States in the 2012 election. In May 2011, he announced he would not be a candidate, but a few weeks later he said he had not completely ruled out the possibility. In December 2011, Trump was suggested as a possible Vice Presidential selection by Michele Bachmann. Bachmann has since suspended her presidential campaign.
Glenn Edward Lee Beck (born February 10, 1964) is an American conservative radio host, vlogger, author, entrepreneur, political commentator and former television host. He hosts the Glenn Beck Program, a nationally syndicated talk-radio show that airs throughout the United States on Premiere Radio Networks. He formerly hosted the Glenn Beck television program, which ran from January 2006 to October 2008 on HLN and from January 2009 to June 2011 on the Fox News Channel. Beck has authored six New York Times–bestselling books. Beck is the founder and CEO of Mercury Radio Arts, a multimedia production company through which he produces content for radio, television, publishing, the stage, and the Internet. It was announced on April 6, 2011, that Beck would "transition off of his daily program" on Fox News later in the year but would team with Fox to "produce a slate of projects for FOX News Channel and FOX News' digital properties". Beck's last daily show on the network was June 30, 2011. In 2012, The Hollywood Reporter named Beck on its Digital Power Fifty list.
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