WBRE-TV is the NBC-affiliated television station for Northeastern Pennsylvania, New York's Eastern Southern Tier and parts of Northern New Jersey that is licensed to Wilkes-Barre. It broadcasts a high definition digital signal on VHF channel 11 from a transmitter at the Penobscot Knob antenna farm near Mountain Top. It can also be seen on Comcast and Service Electric channel 3. On digital cable, there is a high definition signal on Comcast channel 232 and Service Electric channel 503. Owned by the Nexstar Broadcasting Group, the station operates CBS affiliate WYOU (that is owned by Mission Broadcasting) through a joint sales agreement (JSA) and the two share studios on South Franklin Street in downtown Wilkes-Barre. Syndicated programming on WBRE includes: Wheel of Fortune, Jeopardy!, Dr. Oz, and Oprah.

Like other stations in the area, WBRE must rely on repeaters to serve its coverage area. The market is one of the largest (in square miles) east of the Mississippi River and is very mountainous. In addition, Scranton/Wilkes-Barre was a "UHF island" before the digital transition because it is too close to Philadelphia and New York City for VHF analog service. During March 2010, in a cost-cutting move, all owned and operated translators were shut down after Nexstar determined that its VHF signal for WBRE is adequate enough to reach the Wilkes-Barre viewing market. According to nepahdtv.com, this move was met with some dismay from viewers in areas where reception of signals from Penobscot Knob is difficult if not impossible, leaving many people in rural areas without their signal. Despite this, no effort from Nexstar has been made to bring back any of the repeaters.