Trigeminal Ganglion

Latest News for: trigeminal ganglion

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Atlas of Migraine Cell Types Sheds Light on New Therapeutic Targets

Technology Org 30 Mar 2022

While scientists know that migraine and related headaches are caused by activity in a part of the nervous system known as the trigeminal ganglion (TG), it remains unclear which genes and cell types of the TG are involved ... or branch of the trigeminal ganglion,“ said Jochen K.

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The nerve bundle in an elephant's trunk found to be one of the largest known ...

Phys Dot Org 21 Jan 2022

An elephant's trunk is agile and is used for many purposes ... One of the major focus areas was the trigeminal ganglion, which is a network of nerves in the trunk and parts of the face—elephants have two of them ... Leopold Purkart et al, Trigeminal ganglion and sensory nerves suggest tactile specialization of elephants, Current Biology (2022). DOI ... ....

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How my shingles reminded me every day counts

The Jerusalem Post 05 May 2021

I figure it’s just a bug bite. Israeli springtime with its glorious weather and burst of flowers is accompanied by thirsty insects waking up from winter slumber ... My right eye hurts, too ... And all this time, the shingles virus was waiting in the wings, dormant in the ganglia of the spinal cord or the trigeminal ganglion at the base of my skull ... .

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DNA/RNA Vaccines: “Can They Alter Our Own Genetic Codes”

GlobalResearch 13 Apr 2021

Everyone is talking about DNA/RNA vaccines. Can they alter our own genetic codes?. The vaccine lobby says “Never!” I, however — laboring beneath the weight of a Ph.D ... “Well, hardly ever.” ... That’s about it ... It is a known fact that herpes type I, in the latent state, resides in the trigeminal ganglion, inside the skull near the spinal cord ... – Ph.D ... DOI ... DOI.

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Why I Won’t Take the Johnson & Johnson Vaccine — a Scientist’s Perspective

Children's Health Defense 12 Apr 2021

Everyone is talking about DNA/RNA vaccines. Can they alter our own genetic codes?. The vaccine lobby says “Never!” I, however — laboring beneath the weight of a Ph.D ... “Well, hardly ever.” ... That’s about it ... Name* ... It is a known fact that herpes type I, in the latent state, resides in the trigeminal ganglion, inside the skull near the spinal cord.

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Seurat Therapeutics Announces Novel Mechanisms from Rat Migraine Model of Intranasal Insulin-like Growth Factor-1

The Marshall News Messenger 10 Feb 2020

The studies demonstrated that oxidative stress increases calcitonin gene-related peptide (CGRP) expression, a trigeminal system pain pathway mediator associated with migraine; and that intranasal IGF-1 significantly reduces oxidative stress levels and trigeminal ganglion CGRP.

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Rare tumour removed from patient’s skull

Gulf News 27 Jan 2020

Dubai Hospital’s ENT team successfully removed a rare deep tumour located at the base of the skull of a patient in her thirties ... The patient was followed up regularly ... Pterygopalatine fossa schwannomas arise from the maxillary division of the trigeminal nerve, pterygopalatine ganglion, the inferior orbital nerve, and other small communicating nerves.

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Experiencing migraines? Here’s a possible option for treatment

Scottsbluff StarHerald 31 Oct 2019

Migraines are invisible, so it is hard for people who have never had them to understand how debilitating they can be for those who suffer from them ... The nerve that is treated is called the Sphenopalatine Ganglion Nerve (SPG). The SPG is associated with the Trigeminal Nerve, the major nerve involved in headache disorders ... .

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Squarex Announces Positive Results from Completed Phase 2 Study of SQX770 in the Prevention of ...

Odessa American 05 Aug 2019

ST. PAUL, Minn., Aug ... The study was designed to determine if the topical application of SADBE can delay outbreaks of HSV-1 ... FDA ... The natural history of HSV-1 infection leading to herpes labialis is that the virus typically initially infects oral mucosa, and then migrates to sensory neurons and establishes latency, typically in the trigeminal ganglion.

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Biohaven Enrolls First Patient in Phase 2 Clinical Trial of Rimegepant, Oral CGRP Receptor Antagonist, for Treatment Refractory Trigeminal Neuralgia

Pharmiweb 01 Jul 2019

Robert Croop, M.D., Biohaven Chief Development Officer - Neurology , commented, "CGRP is an important mechanistic target that has been implicated in a variety of diseases.  Emerging evidence suggests that aberrant release of CGRP from the trigeminal ganglion plays a critical ...

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Biohaven Enrolls First Patient in Phase 2 Clinical Trial of Rimegepant, Oral CGRP Receptor Antagonist, ...

The Record 01 Jul 2019

Emerging evidence suggests that aberrant release of CGRP from the trigeminal ganglion plays a critical role in the development of pain syndromes such as trigeminal neuralgia ... Researchers will evaluate the efficacy and safety of rimegepant in treating trigeminal neuralgia in patients who failed to respond adequately to pharmacotherapy.

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Global Market Report on Bioelectronic Medicine 2019-2029 From IDTechEx Research

Market Watch 21 Dec 2018

Included in this report are devices that stimulate the spinal cord (including dorsal root ganglion), brain, vagus nerve, sacral nerve, tibial nerve, trigeminal nerve, and many others ... Spinal Cord and Dorsal Root Ganglion Stimulation ... Trigeminal Nerve Stimulation.

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New Migraine Medication Could Help Those Who've Tried Everything Else

IFL Science 19 Apr 2018

We now have evidence that triptans inhibit release of CGRP from overactive nerves in the trigeminal ganglion – a collection of nerve fibers that innervate the head, eye, and jaw ... These prophylactic agents must be taken every day and have mixed success. Furthermore, they may cause side effects as debilitating as the migraines themselves ... .

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Sosei Regains Worldwide Rights from Teva to Develop and Commercialize Novel Small Molecule CGRP Antagonists for Migraine and Other Severe Headaches

Market Watch 13 Mar 2018

Sosei Group (“Sosei” or the “Company”; TOKYO Mothers Index ... The first dosing in a Phase 1 clinical trial in healthy volunteers was expected in late 2018 ... Notes to Editors ... CGRP is found in small to medium sized neurons in the trigeminal ganglion of the brain and mediates its activity through G protein-coupled receptors located throughout the body ... or.

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Photobiomodulation Shows Great Promise for Athletes, Chronic Pain Syndromes and More

Mercola 12 Nov 2017

So, if you treat along the nerves and over the neck — over the cell bodies for the trigeminal ganglion, which are located in the neck — then yes, you can reduce dental pain,” he says.