Ipratropium bromide

Ipratropium bromide, sold under the trade name Atrovent among others, is a medication that opens up the medium and large airways in the lungs. It is used to treat the symptoms of chronic obstructive pulmonary disease and asthma. It is used by inhaler or nebulizer. Onset of action is typically within 15 to 30 minutes and lasts for three to five hours.

Common side effects include dry mouth, cough, and inflammation of the airways. Potentially serious side effects include urinary retention, worsening spasms of the airways, and a severe allergic reaction. It appears to be safe in pregnancy and breastfeeding. Ipratropium is an anticholinergic which works by causing smooth muscles to relax.

Ipratropium bromide was developed in Germany in 1976. It was approved for medical use in the United States in 1986. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. Ipratropium is available as a generic medication. The wholesale price is about 6.60 USD for a 200 dose inhaler. In the United States a month worth of medication is between 100 and 200 USD.