Rüsselsheim is the largest town in the Groß-Gerau district in the Rhein-Main region of Germany. It is one of seven special status towns in Hesse and is located on the Main, only a few kilometres from its mouth in Mainz. The suburbs of Bauschheim and Königstädten are included in Rüsselsheim. Rüsselsheim has attained international recognition through the presence of the German car company Adam Opel AG.

Rüsselsheim emerged from a settlement of the Count of Katzenelnbogen.

The name of the town evolved over the course of time:

In the year 1435 the high noble Count John IV of Katzenelnbogen was first to cultivate Riesling in Rüsselsheim. His administrator bought new vines for 22 Schilling documented in the annual reports. in the following years Riesling showed up down the river Rhine and up the River Mosel. Rüsselsheim's comeback in the history of wine took place in 18th and 19th century, when famous wine-growing estates in the Rheingau recultivated their vineyards with vines of the Rüsselsheim and Flörsheim Area (Allendorf, Rheingauer Weinbauverband EV 1980). After the First World War viticulture disappeared in Rüsselsheim. In 1980 the mayor of Rüsselsheim Dr. Storsberg initiated a memory vineyard near the castle celebrating 550 Years of Riesling. This vineyard still exists.