Ponsacco is a comune (municipality) in the Province of Pisa in the Italian region Tuscany, located about 50 km southwest of Florence and about 20 km southeast of Pisa. As of 31 December 2004, it had a population of 13,353 and an area of 19.9 km².

The municipality of Ponsacco contains the frazioni (subdivisions, mainly villages and hamlets) Le Melorie, Val di Cava, and Camugliano.

Ponsacco borders the following municipalities: Capannoli, Lari, Pontedera.

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Giuseppe Di Vittorio, also known under the pseudonym Nicoletti (August 12, 1892 — November 3, 1957), was an Italian syndicalist trade unionist and communist politician, one of the most influential leaders of the labor movement after World War I.

He was born at Cerignola, Apulia, into a family of poor agricultural day laborers. As an autodidact, Di Vittorio became active in the socialist movement from adolescence: at fifteen, he was a member of the Socialist Youth Circle in Cerignola, and, in 1911, moved to lead the Camera del Lavoro in Minervino Murge, and then the one in Bari. Giuseppe Di Vittorio was among the most influential union leaders in the history of the labor movement, leading the Confederazione Generate Italiana dei Lavoratori (CGIL) in its refounding after Fascism and the powerful World Federation of Trade Unions(FSM) after World War II. After his father's death Di Vittorio was forced to leave school and work as a day laborer. He joined the May 1904 general strike, an event during which five workers were killed by troops in Cerignola. Di Vittorio was strongly influenced by the growth of peasants' organizations and the spread of socialist ideas, giving rise to his participation in the local young socialist organization in Cerignola. He was radicalized by affiliating with the national Federazione Giovanile Socialista (Federation of Young Socialists), an organization led by syndicalists in opposition to the official Socialist Party Youth Federation.