The AFC South is a division of the National Football League's American Football Conference. It was created before the 2002 season when the league realigned divisions after expanding to 32 teams. Since its creation, the division has had the same four members: Houston Texans, Indianapolis Colts, Jacksonville Jaguars, and Tennessee Titans.

Before the 2002 season, the Texans did not exist, the Colts belonged to the AFC East, and the Titans and Jaguars were members of the AFC Central. Indianapolis, Tennessee, and Jacksonville all won multiple division titles and wild card berths in their prior respective divisions.

Entering 2012, the Colts hold a 453–410–7 record and a 19–20 playoff record with three NFL league crowns, four Super Bowl appearances and two wins. The Titans hold a record of 386–396–6 with a playoff record of 14–19, including two AFL championships and the loss in Super Bowl XXXIV. The Jaguars hold a 138–134 record and a 5–6 playoff record. The Texans made the playoffs for the first time in their ten-season existence in 2011 and hold a 65–95 record and a 1–1 playoff record.

AFC is an abbreviation that may refer to:

South is a noun, adjective, or adverb indicating direction or geography.

South is one of the four cardinal directions or compass points. It is the opposite of north and is perpendicular to east and west.

By convention, the bottom side of a map is south.

To go south using a compass for navigation, set a bearing or azimuth of 180°.

True south is the direction towards the southern end of the axis about which the earth rotates, called the South Pole. The South Pole is located in Antarctica. Magnetic south is the direction towards the south magnetic pole, some distance away from the south geographic pole.

The word south is derived from the name of one of the four dwarves in Norse mythology, Norðri, Suðri, Austri and Vestri, who each represented one of the directions of the world. The etymology of South can be traced back to the Old English word suth, related to the Old High German word sund, and perhaps sunne in Old English with sense of "the region of the sun."