Amphipolis (Ancient Greek: Ἀμφίπολις: Amphípolis) was an ancient Greek city in the region once inhabited by the Edoni people in the present-day region of Central Macedonia. It was built on a raised plateau overlooking the east bank of the river Strymon where it emerged from Lake Cercinitis, about 3 m. from the Aegean Sea. Founded in 437 BC, the city was finally abandoned in the 8th century AD. The present village Amfipoli (Greek: Αμφίπολη), named after the ancient city, occupies the site. It is a municipality in the Serres regional unit of Macedonia, Greece. The seat of the municipality is Rodolivos.
Archaeology has uncovered remains at the site dating to approximately 3000 BC. Due to the strategic location of the site it was fortified from very early.In the 8th and 7th century BC the site of Amphipolis was ruled by Illyrian tribes.Xerxes I of Persia passed during his invasion of Greece of 480 BC and buried alive nine young men and nine maidens as a sacrifice to the river god.[citation needed] Near the later site of Amphipolis Alexander I of Macedon defeated the remains of Xerxes' army in 479 BC.