BID

Bid or BID may refer to:

Offer

Places

Science, medicine and technology

BH3 interacting-domain death agonist

The BH3 interacting-domain death agonist, or BID, gene is a pro-apoptotic member of the Bcl-2 protein family. Bcl-2 family members share one or more of the four characteristic domains of homology entitled the Bcl-2 homology (BH) domains (named BH1, BH2, BH3 and BH4), and can form hetero- or homodimers. Bcl-2 proteins act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.

Interactions

BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into organelle membranes, primarily the outer mitochondrial membrane. Bax is believed to interact with, and induce the opening of the mitochondrial voltage-dependent anion channel, VDAC. Alternatively, growing evidence suggest that activated Bax and/or Bak form an oligomeric pore, MAC in the outer membrane. This results in the release of cytochrome c and other pro-apoptotic factors (such as SMAC/DIABLO) from the mitochondria, often referred to as mitochondrial outer membrane permeabilization, leading to activation of caspases. This defines BID as a direct activator of Bax, a role common to some of the pro-apoptotic Bcl-2 proteins containing only the BH3 domain.

Portex

Portex (or BID/50/1) was a British cipher machine. A rotor machine, the device used eight rotors each with a tyre ring and an insert. The machine was used mainly by the secret services from the late 1940s to the early 1950s.

See also

References

External links

University of Missouri–Kansas City

The University of Missouri–Kansas City (UMKC) is a public research university located in Kansas City, Missouri, United States. It is a part of the University of Missouri System. Its main campus is in Kansas City's Rockhill neighborhood east of the Country Club Plaza. The university's enrollment is more than 15,700 in 2014.

History

Lincoln and Lee University

The school has its roots in the Lincoln and Lee University movement first put forth by the Methodist Church and its Bishop Ernest Lynn Waldorf in the 1920s. The proposed university (which was to honor Abraham Lincoln and Robert E. Lee) was to be built on the Missouri-Kansas border at 75th and State Line Road, where the Battle of Westport (the largest battle west of the Mississippi River during the American Civil War) took place. The centerpiece of the school was to be a National Memorial marking the tomb of an unknown Union soldier and unknown Confederate soldier. Proponents of the school said it would be a location "where North met South and East met West." The Methodist interest reflected the church's important role in the development of the Kansas City area through the Shawnee Methodist Mission which was the second capital of Kansas.

Nyx

Nyx (English /ˈnɪks/;Ancient Greek: Νύξ, "Night";Latin: Nox) is the Greek goddess (or personification) of the night. A shadowy figure, Nyx stood at or near the beginning of creation, and mothered other personified deities such as Hypnos (Sleep) and Thanatos (Death), with Erebus (Darkness). Her appearances are sparse in surviving mythology, but reveal her as a figure of such exceptional power and beauty, that she is feared by Zeus himself.

Mythology and literature

Hesiod

In Hesiod's Theogony, Nyx is born of Chaos. With Erebus (Darkness), Nyx gives birth to Aether (Brightness) and Hemera (Day). Later, on her own, Nyx gives birth to Moros (Doom, Destiny), Ker (Destruction, Death), Thanatos (Death), Hypnos (Sleep), the Oneiroi (Dreams), Momus (Blame), Oizys (Pain, Distress), the Hesperides, the Moirai (Fates), the Keres, Nemesis (Indignation, Retribution), Apate (Deceit), Philotes (Friendship), Geras (Old Age), and Eris (Strife).

In his description of Tartarus, Hesiod locates there the home of Nyx, and the homes of her children Hypnos and Thanatos. Hesiod says further that Nyx's daughter Hemera (Day) left Tartarus just as Nyx (Night) entered it; continuing cyclicly, when Hemera returned, Nyx left. This mirrors the portrayal of Ratri (night) in the Rigveda, where she works in close cooperation but also tension with her sister Ushas (dawn).

Night (book)

Night (1960) is a work by Elie Wiesel about his experience with his father in the Nazi German concentration camps at Auschwitz and Buchenwald in 1944–45, at the height of the Holocaust toward the end of the Second World War. In just over 100 pages of sparse and fragmented narrative, Wiesel writes about the death of God and his own increasing disgust with humanity, reflected in the inversion of the parent–child relationship as his father declines to a helpless state and Wiesel becomes his resentful teenage caregiver. "If only I could get rid of this dead weight ... Immediately I felt ashamed of myself, ashamed forever." In Night everything is inverted, every value destroyed. "Here there are no fathers, no brothers, no friends," a Kapo tells him. "Everyone lives and dies for himself alone."

Wiesel was 16 when Buchenwald was liberated by the United States Army in April 1945, too late for his father, who died after a beating while Wiesel lay silently on the bunk above for fear of being beaten too. He moved to Paris after the war, and in 1954 completed an 862-page manuscript in Yiddish about his experiences, published in Argentina as the 245-page Un di velt hot geshvign ("And the World Remained Silent"). The novelist François Mauriac helped him find a French publisher. Les Éditions de Minuit published 178 pages as La Nuit in 1958, and in 1960 Hill & Wang in New York published a 116-page translation as Night.

Gazpacho (band)

Gazpacho are an art rock band from Oslo, Norway. The original core band of Jan-Henrik Ohme (vocals), Jon-Arne Vilbo (guitars) and Thomas Andersen (keyboards, programming, producer) started making music together in 1996 and the band has since expanded with Mikael Krømer (violin, co-producer), Lars Erik Asp (drums) and Kristian Torp (bass).

Gazpacho's music has been described by one critic as being "classical post ambient nocturnal atmospheric neo-progressive folk world rock". The music has been compared to A-ha, Radiohead, Marillion and Porcupine Tree.

Without the backing of a major label, Gazpacho is one of many bands now using the Internet to promote their music, specifically their own website and its forum, online shopping and MySpace. This allows the band to hold down full-time jobs, yet still manage to release an album a year with total artistic control over their compositions and distribution.

History

The Early Years (1996–2001)

Childhood friends Jon-Arne Vilbo and Thomas Andersen had played together in a band called Delerium before, which in their own words "whittled away." After several years of separation, the two friends met again and started making music together again. Andersen had met Jan-Henrik Ohme through his work as radio commercial producer and brought him into the jam sessions, which laid the foundation for Gazpacho as it exists today.