Nuclear receptor coactivator 2

The nuclear receptor coactivator 2 also known as NCoA-2 is a protein that in humans is encoded by the NCOA2 gene. NCoA-2 is also frequently called glucocorticoid receptor-interacting protein 1 (GRIP1), steroid receptor coactivator-2 (SRC-2), or transcriptional mediators/intermediary factor 2 (TIF2).

Function

NCoA-2 is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity. NCOA2 is recruited to DNA promotion sites by ligand-activated nuclear receptors. NCOA2 in turn acetylates histones, which makes downstream DNA more accessible to transcription. Hence, NCOA2 assists nuclear receptors in the upregulation of DNA expression.

GRIP1 is a transcriptional co-activator of the glucocorticoid receptor and interferon regulatory factor 1 (IRF1).

Interactions

Nuclear receptor coactivator 2 has been shown to interact with:

Titanium tetrafluoride

Titanium(IV) fluoride is the inorganic compound with the formula TiF₄. It is a white hygroscopic solid. In contrast to the other halides of titanium, it adopts a polymeric structure consisting of octahedral Ti centres.

Preparation

The traditional method involves treatment of titanium tetrachloride with excess hydrogen fluoride, and purification by sublimation:

References

Titanium(III) fluoride

Titanium(III) fluoride (TiF₃) is a chemical compound of titanium in its oxidation state +3. It can be obtained by the reaction of titanium(III) oxide with hydrofluoric acid (this reaction reverses if TiF₃ is dissolved in excess water), or by reduction of titanium tetrafluoride.

Conditions/substances to avoid are: strong acids, strong oxidizers.

References

Rice wine

Rice wine, also known as mijiu, is an eastern alcoholic beverage made from rice, originally from China. Unlike European wine, which is made by fermentation of naturally occurring sugars in sweet grapes and other fruit, rice wine is made from the fermentation of rice starch that has been converted to sugars. The process is somewhat similar to the mashing process used in beer and whiskey production but differs in the source of the enzymes that convert starch to sugars. In rice and other cereal wines, microbes are the source of the enzymes whereas beer, ale and whiskey production utilizes the enzymes naturally occurring in sprouted barley.

Rice (novel)

Rice is a novel by Chinese author Su Tong.

Plot

The story is based during the flood days in 1930s in China, when people immigrated from the countryside to the urban areas in search of work. This is also a story about Five Dragons, a poor but haughty country boy, chancing his fortune in the city and the humiliation he faces as soon as he reaches the city.

He is a typical man hungry for wealth but with an insatiable thirst for pleasure, especially sex. His master has two daughters, "Cloud Weave" and "Cloud Silk". Cloud Weave is very much like Five Dragons, and shares his sexual appetite. She is a mistress to a local mafia.

Five Dragons marries her and inherits the property of his master: his rice emporium and his whole business. But men tire easily of their playthings, particularly in this wayward family. Fidelity is an unrecognised term for them.

This story also shows how infidelity passes from one generation to another in this family.

Rice (film)

Rice (Korean: 쌀, translit. Ssal) is a 1963 South Korean drama film directed by Shin Sang-ok. The film was selected as the South Korean entry for the Best Foreign Language Film at the 39th Academy Awards, but was not accepted as a nominee.

Cast

See also

References

External links