Anaphylaxis

Anaphylaxis is defined as "a serious allergic reaction that is rapid in onset and may cause death". It typically results in a number of symptoms including an itchy rash, throat swelling, and low blood pressure. Common causes include insect bites, foods, and medications.

On a pathophysiologic level, anaphylaxis is caused by the release of mediators from certain types of white blood cells triggered either by immunologic or non-immunologic mechanisms. It is diagnosed based on the presenting symptoms and signs. The primary treatment is injection of epinephrine, with other measures being complementary.

Worldwide 0.05–2% of people are estimated to have anaphylaxis at some point in their life and rates appear to be increasing. The term comes from the Greek words ἀνά ana, against, and φύλαξις phylaxis, protection.

Anaphylaxis typically presents with many different symptoms over minutes or hours with an average onset of 5 to 30 minutes if exposure is intravenous and 2 hours for foods. The most common areas affected include: skin (80–90%), respiratory (70%), gastrointestinal (30–45%), heart and vasculature (10–45%), and central nervous system (10–15%) with usually two or more being involved.

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The body of an unidentified person was discovered Tuesday afternoon in the Lake Hunter section of Lakeland, Fla. inside the mouth of an eight-foot alligator, CBS News reported.Lakeland police spokesman Gary Gross told CBS affiliate WTSP officers responded to a call concerning an alligator with a body in its mouth. Officers were able to retrieve the body, and Gross said a trapper was called to capture the eight-foot reptile....

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Edit Science Daily 07 Jun 2016

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Israeli Prime Minister Benjamin Netanyahu greets supporters at the party's election headquarters In Tel Aviv, Wednesday, March 18, 2015.

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Edit WorldNews.com 07 Jun 2016

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Edit WorldNews.com 07 Jun 2016

Article by WN.com Correspondent Dallas DarlingSenator Bernie Sanders has Hillary Clinton on the ropes. Indeed, on Tuesday the former U.S. Secretary of State will be in the fight of her life as the two Democrat candidates battle in California’s delegate-rich primary. In effect, the Establishment and Superdelegates are already questioning just how formidable their anointed candidate really is ... But in politics, perception is reality....

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Edit WorldNews.com 07 Jun 2016

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How bee stings can be DEADLY even if you've been stung before

Edit The Daily Mail 07 Jun 2016

The latest NHS figures show there were 4,000 hospital admissions for anaphylaxis last year - which can cause swollen airways and breathing difficulties - up nearly 10 per cent from 2010/11 ... ....

Doc in dock as Tamil Nadu medico dies day after hair transplant

Edit The Times of India 07 Jun 2016

Chennai. A final-year medical student from the Madras Medical College died a day after undergoing a hair transplant procedure at a salon in Nungambakkam more than a fortnight ago ... "Hospital reports said that he died soon after admission due to multi-organ failure triggered by delayed anaphylaxis and toxic syndrome," said Dr Senthil. Anaphylaxis is a strong allergic reaction which can been triggered by anaesthesia ... RELATED....

UPDATE 1-FDA rejects Adamis' emergency drug for severe allergic reaction

Edit Reuters 06 Jun 2016

June 6 (Reuters) - Adamis Pharmaceuticals Corp said on Monday the U.S. Food and Drug Administration rejected its emergency treatment for acute anaphylaxis, a severe allergic reaction, for the second time. ....

FDA rejects Adamis' emergency drug for severe allergic reaction

Edit Reuters 06 Jun 2016

(Reuters) - Adamis Pharmaceuticals Corp said on Monday the U.S. Food and Drug Administration rejected its emergency treatment for acute anaphylaxis, a severe allergic reaction, for the second time. ....

FDA rejects Adamis' emergency treatment for severe allergic reaction

Edit Reuters 06 Jun 2016

June 6 (Reuters) - Adamis Pharmaceuticals Corp said the U.S. Food and Drug Administration rejected its emergency treatment for a severe, potentially fatal allergic reaction or acute anaphylaxis. ....

Adamis Pharmaceuticals (ADMP) Stock Plummeting on FDA Drug Rejection

Edit The Street 06 Jun 2016

The prefilled single dose syringe is for the treatment of the severe allergic reaction known as anaphylaxis ... This is the second time the FDA rejected the company's epinephrine injection ... ....

Adamis Pharmaceuticals Receives Complete Response Letter From FDA For Its Epinephrine Pre-Filled Syringe NDA

Edit Stockhouse 06 Jun 2016

Food and Drug Administration (FDA) regarding its New Drug Application (NDA) Epinephrine Injection USP 1.1000 0.3mg Pre-filled Single Dose Syringe (PFS) product.  PFS is for the emergency treatment of acute anaphylaxis, which is a severe allergic reaction. A CRL is issued by the FDA's Center for Drug Evaluation and Research when it ......

Adamis Pharmaceuticals Receives Complete Response Letter From FDA For Its Epinephrine Pre-Filled Syringe NDA (Adamis Pharmaceuticals Corporation)

Edit Public Technologies 06 Jun 2016

(Source ... PFS is for the emergency treatment of acute anaphylaxis, which is a severe allergic reaction ... Dr. Dennis J ... The Company's current specialty pharmaceutical product candidates include the Epinephrine Injection PFS syringe product for use in the emergency treatment of anaphylaxis, APC-1000 and APC-5000 for the treatment of asthma and chronic obstructive pulmonary disease, and APC-2000 for the treatment of bronchospasms ... (noodl....

Pay-out for Irish patient who was 'too hairy' for defibrillation

Edit Belfast Telegraph 06 Jun 2016

An Irish man whose excessive chest hair impeded repeated attempts by A&E; doctors to get his heart pumping again sued the hospital and was paid compensation ... Share Go To ... No further details of the case were disclosed. The agency also dealt with claims arising from two deaths, including that of a patient who had no known drug allergies but who developed anaphylaxis, requiring adrenaline to save their life ... Read more ... Irish Independent....

New Data at CMSC Assess Real-World Impact of Rebif® (interferon beta-1a) in People with Relapsing MS (EMD Serono Inc)

Edit Public Technologies 06 Jun 2016

(Source. EMD Serono Inc) b3365cae-ecdf-4756-8c09-34d44e2bbc70.pdf. News Release Your Contact. Erin-Marie Beals 1-781-681-2850. June 2, 2016 New Data at CMSC Assess Real-World Impact of Rebif® (interferon beta-1a) in People with Relapsing MS. Data compare Rebif vs ... Tel.. 1-800-283-8088. 1 of 4 ... C ... C ... Anaphylaxis and other allergic reactions (some severe) have been reported as a rare complication of Rebif. Discontinue Rebif if anaphylaxis occurs....

Hostess recall for life-threatening allergy: Full list of recalled Hostess foods

Edit The Examiner 06 Jun 2016

A Hostess recall of 710,000 cases of Hostess snack cakes and donuts was issued after children suffered immediate allergic reactions. Hostess recalled the snacks when an analysis of the flour used for the snacks showed that the children’s allergic reaction was caused by peanuts ... A person with a peanut allergy or other food allergies can experience a severe and life-threatening allergic reaction called anaphylaxis ... Variety. Item UPC. Batch....

Takeda to Present New Data at the American Diabetes Association's 76th Scientific Sessions (Takeda Pharmaceutical Co Ltd)

Edit Public Technologies 06 Jun 2016

(Source. Takeda Pharmaceutical Co Ltd). Eight abstract presentations include new analyses from the EXAMINE trial and real-world databases. Osaka, Japan, 6 June, 2016 - Takeda Pharmaceuticals Company Limited [TSE ... AlogliptIN vs ... Posters ... Alogliptin is contraindicated in patients with a history of serious hypersensitivity reaction to alogliptin-containing products such as anaphylaxis, angioedema, or severe cutaneous adverse reactions ... Takeda....

New Data Demonstrate Safety Of Long-Term, Around-The-Clock Treatment With BELBUCA™ (Buprenorphine) Buccal Film For Chronic Pain (Endo International plc)

Edit Public Technologies 03 Jun 2016

(Source. Endo International plc). Findings also show sustained pain relief with BELBUCA™treatment for up to 48 weeks among ... ENDP) (TSX ... (NASDAQ. BDSI) ... About BELBUCA™ ... WARNING ... Significant respiratory depression Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment Known or suspected gastrointestinal obstruction, including paralytic ileus Hypersensitivity (eg, anaphylaxis) to buprenorphine....

Anaphylaxis

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You can search using any combination of the items listed below.

How bee stings can be DEADLY even if you've been stung before

Doc in dock as Tamil Nadu medico dies day after hair transplant

UPDATE 1-FDA rejects Adamis' emergency drug for severe allergic reaction

FDA rejects Adamis' emergency drug for severe allergic reaction

FDA rejects Adamis' emergency treatment for severe allergic reaction

Adamis Pharmaceuticals (ADMP) Stock Plummeting on FDA Drug Rejection

Adamis Pharmaceuticals Receives Complete Response Letter From FDA For Its Epinephrine Pre-Filled Syringe NDA

Adamis Pharmaceuticals Receives Complete Response Letter From FDA For Its Epinephrine Pre-Filled Syringe NDA (Adamis Pharmaceuticals Corporation)

Pay-out for Irish patient who was 'too hairy' for defibrillation

New Data at CMSC Assess Real-World Impact of Rebif® (interferon beta-1a) in People with Relapsing MS (EMD Serono Inc)

Hostess recall for life-threatening allergy: Full list of recalled Hostess foods

Takeda to Present New Data at the American Diabetes Association's 76th Scientific Sessions (Takeda Pharmaceutical Co Ltd)

New Data Demonstrate Safety Of Long-Term, Around-The-Clock Treatment With BELBUCA™ (Buprenorphine) Buccal Film For Chronic Pain (Endo International plc)