Major (given name)

Major is a given name which may refer to:

See also

Secrets (post-hardcore band)

Secrets (stylized as SECRETS) is an American post-hardcore band from San Diego, California, formed in 2010. After being signed to Rise Records in 2011, Secrets released their debut full-length album, The Ascent, in January 2012. The record debuted at #3 on the Billboard Heatseekers Chart and became the first Velocity Records release to appear on the Billboard Top 200, debuting at #185.

After going through line-up changes in 2013, the band released their second album, Fragile Figures in July. The album was a success, selling over 10,000 copies in the first month and charting at #59 on the Billboard 200 chart.

History

Formation and The Ascent (2010–2012)

Secrets was formed from ex-A City Serene members, Xander Bourgeois, Marc Koch, Joe English, and Michael Sherman. The original line up of A City Serene soon dispersed after they were involved in a serious car accident, which left one member in a coma. They reformed as Secrets in 2010, and added Richard Rogers as their clean vocalist and rhythm guitarist. The band was quickly signed to Rise Records imprint, Velocity Records. Though they initially planned to release an EP, the band went ahead with a full-length album, The Ascent. This album was produced by Tom Denney, formerly of A Day to Remember.

Secrets (Allison Crowe album)

Secrets, released in 2004 (see 2004 in music), is the second studio album released by Allison Crowe and her first full-length CD. Following the dissolution of her trio, Crowe recorded this solo, singer-songwriter, collection in Nanaimo, British Columbia. She engineered the recording and assisted with production alongside Rainer Willeke of the Victoria, Canada-based r'n'b combo, Soul Station. Performing all vocals (lead and harmonies), piano and keyboards Crowe added acoustic guitar tracks and percussive 'thumps'.

Secrets contains 'old' fan favourites (some of which are radically redefined from earlier performances), newly penned songs, and a pair of personal picks from other artists: Counting Crows' "Raining in Baltimore" ~ the first song performed by Crowe when she launched her career as a singer-songwriter in the mid-'90s; and "Joan of Arc", a poem song from the pen of Leonard Cohen.

Track listing

Secrets (Toni Braxton album)

Secrets is the second studio album by American singer Toni Braxton, released on June 18, 1996 by LaFace Records and Arista Records. The album was nominated for Best Pop Album at the 1997 Grammy Awards. Secrets has been certified octuple platinum by the Recording Industry Association of America (RIAA) and has sold 5,364,000 copies in the United States. Worldwide, the album has sold over 15 million copies. In support of the album, Braxton embarked on the Secrets Tour, playing dates in North America and Europe from August 1996 to October 1997.

Composition

The album's first song "Come On Over Here" is a "finger-poppingly upbeat", sultry groove track produced by Tony Rich. It was described as "a neo-Motown composition. The second track and lead single, the airily funky "You're Makin' Me High", was produced by Babyface and Bryce Wilson. It was also nominated for Best R&B Song at the Grammy Awards. The third track "There's No Me Without You" is a romantic song. The fourth track and second single "Un-Break My Heart" is a ballad written by Diane Warren. She played the finished song to Arista Records president Clive Davis. He thought it would be perfect for Toni Braxton. With background vocals by Shanice Wilson and produced by David Foster, the song spent 11 weeks at number one at pop and 14-week stay at number one on adult contemporary radio stations in late 1996. It also won a 1997 Grammy for Best Female Pop Vocal Performance. It is a song of blistering heartbreak, as Braxton sings to her former lover, begging him to return to her and undo all the pain he has cause. The fifth track "Talking in His Sleep" is about adultery.

MEN1

Menin is a protein that in humans is encoded by the MEN1 gene. Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome).

In vitro studies have shown that menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD. However, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Two variants of the shorter transcript have been identified where alternative splicing affects the coding sequence. Five variants where alternative splicing takes place in the 5' UTR have also been identified.

History

In 1988, researchers at Uppsala University Hospital and the Karolinska Institute in Stockholm mapped the MEN1 gene to the long arm of chromosome 11. The gene was finally cloned in 1997.

Genomics

The gene is located on long arm of chromosome 11 (11q13) between base pairs 64,570,985 and 64,578,765. It has 10 exons and encodes a 610-amino acid protein.

Apocalypse (chess variant)

Apocalypse is a chess variant invented by C. S. Elliott in 1976. The players each start with two horsemen and five footmen on a 5×5 board. The two sides make their moves simultaneously.

The game was featured in Issue 53 of Games & Puzzles magazine.

Game rules

The starting setup is as shown. Horsemen and footmen move and capture the same as knights and pawns in chess, except footmen do not have a double-step option on their first move. For each turn, each player secretly writes down his move, then the players simultaneously declare them. The following rules apply:

A footman promotes to horseman when reaching the last rank, but only when the player has less than two horsemen. Otherwise the player must redeploy the footman to any vacant square.

2012 phenomenon

The 2012 phenomenon was a range of eschatological beliefs that cataclysmic or otherwise transformative events would occur on or around 21 December 2012. This date was regarded as the end-date of a 5,126-year-long cycle in the Mesoamerican Long Count calendar, and as such, festivities to commemorate the date took place on 21 December 2012 in the countries that were part of the Mayan civilization (Mexico, Guatemala, Honduras, and El Salvador), with main events at Chichén Itzá in Mexico, and Tikal in Guatemala.

Various astronomical alignments and numerological formulae were proposed as pertaining to this date. A New Age interpretation held that the date marked the start of a period during which Earth and its inhabitants would undergo a positive physical or spiritual transformation, and that 21 December 2012 would mark the beginning of a new era. Others suggested that the date marked the end of the world or a similar catastrophe. Scenarios suggested for the end of the world included the arrival of the next solar maximum, an interaction between Earth and the black hole at the center of the galaxy, or Earth's collision with a planet called Nibiru.