HMGA2
High-mobility group AT-hook 2, also known as HMGA2, is a protein that, in humans, is encoded by the HMGA2 gene.
Function
This gene encodes a protein that belongs to the non-histone chromosomal high-mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhanceosome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with lipomas suggests a role in adipogenesis and mesenchymal differentiation. A gene knock-out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
The expression of HMGA2 in adult tissues is commonly associated with both malignant and benign tumor formation, as well as certain characteristic cancer-promoting mutations. Homologous proteins with highly conserved sequences are found in other mammalian species, including lab mice (Mus musculus).
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O By God
by: Mika(Rumchika Rika Pika Rika Rum Pup Chor
Tika Lika Chika Lika Lak Tak Chor
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Siya Merano Me' Sano Fina) 2
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Jo Bandhe Hai Pasand Mujhako
O By God, Bole Jo Teri Meri Jodi Khuda Ne Khud Jodi
O By Rajamand Mujhako) 2
Ho Aata Hoon Jab Saamane Tere, Leta Hoon Sapano Mein Phere
Saanson Mein Aur Dil Mein Mere Baje Yeh Shehanaayi
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Baandhe Nigaaho Ne Mohabbat Ke Dhaage, Laage Tu Mera Mujhe) 2
Ho Chaahat Ne Li Hai Angdaayi, Dur Huyi Saari Tanhaayi
Dil Ne Dil Se Taal Milaayi, Baje Yeh Shehanaayi
Baje Yeh Shehanaayi
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Tika Lika Chika Lika Lak Tak Chor
Rumchika Rika Pika Rika Rum Pup Chor
Siya Merano Me' Sano Fina) 2
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Kissa Jawaani Ka Jawaan Tum Se Hain Na, Hain Na Bata Tu Mera) 2
Ho Tu Meri Kismat Ka Taara, Hota Hoon Lo Aaj Tumhaara
Dil Ne Jab Jab Tumhe Pukaara, Baje Yeh Shehanaayi
O By God, Chaahe Mujhe Jo Chori Chori Mohabbaton Ki Dori
Jo Bandhe Hai Pasand Mujhako
O By God, Bole Jo Teri Meri Jodi Khuda Ne Khud Jodi
O By Rajamand Mujhako
Ho Aata Hoon Jab Saamane Tere, Leta Hoon Sapano Mein Phere
Saanson Mein Aur Dil Mein Mere Baje Yeh Shehanaayi