- published: 06 Apr 2015
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Cancer research is basic research into cancer in order to identify causes and develop strategies for prevention, diagnosis, treatments and cure.
Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatment. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, Immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as immunotherapy and gene therapy.
This type of research involves many different disciplines including genetics, diet, environmental factors (i.e. chemical carcinogens). In regard to investigation of causes and potential targets for therapy, the route used starts with data obtained from clinical observations, enters basic research, and, once convincing and independently confirmed results are obtained, proceeds with clinical research, involving appropriately designed trials on consenting human subjects, with aim to test safety and efficiency of the therapeutic intervention method. Important part of basic research is characterization of the potential function of mechanisms of carcinogenesis, in regard to the types of genetic and epigenetic changes that are associated with cancer development. The mouse is often used as a mammalian model for manipulation of the function of genes that play a role in tumor formation, while basic aspects of tumor initiation, such as mutagenesis, are assayed on cultures of bacteria and mammalian cells.
Joseph Robinette "Joe" Biden, Jr. (pronunciation: /ˈdʒoʊsɨf rɒbɨˈnɛt ˈbaɪdən/; born November 20, 1942) is the 47th and current Vice President of the United States, serving under President Barack Obama. A Democrat, he was a United States Senator from Delaware from January 3, 1973 until his resignation on January 15, 2009, following his election to the Vice Presidency.
Biden was born in Scranton, Pennsylvania and lived there for ten years before moving to Delaware. He became an attorney in 1969, and was elected to a county council in 1970. Biden was first elected to the Senate in 1972 and became the sixth-youngest senator in U.S. history. He was re-elected to the Senate six times, was the fourth most senior senator at the time of his resignation, and is the 15th-longest serving Senator in history. Biden was a long-time member and former chairman of the Foreign Relations Committee. His strong advocacy helped bring about U.S. military assistance and intervention during the Bosnian War. He opposed the Gulf War in 1991. He voted in favor of the Iraq War Resolution in 2002, but later proposed resolutions to alter U.S. strategy there. He has also served as chairman of the Senate Judiciary Committee, dealing with issues related to drug policy, crime prevention, and civil liberties, and led creation of the Violent Crime Control and Law Enforcement Act and Violence Against Women Act. He chaired the Judiciary Committee during the contentious U.S. Supreme Court nominations of Robert Bork and Clarence Thomas.