College lacrosse refers to lacrosse played by student athletes at colleges and universities in the United States and Canada. In both countries, men's field lacrosse and women's lacrosse are played in both the varsity and club levels. College lacrosse in Canada is sponsored by the Canadian University Field Lacrosse Association, while in the United States, varsity men's and women's lacrosse is sponsored by the National Collegiate Athletic Association (NCAA).

In the U.S., as of the 2011-12 academic year, there were 61 NCAA-sanctioned Division I men's lacrosse teams, 46 Division II men's lacrosse teams and 189 Division III men's lacrosse teams, as well as 92 Division I women's lacrosse teams, 67 Division II women's lacrosse teams, and 216 Division III women's lacrosse teams. There were also 28 men's programs and 17 women's programs at at two-year community colleges organized by the National Junior College Athletic Association (NJCAA) and a growing number of National Association of Intercollegiate Athletics (NAIA) four-year small college programs.