Bless you, or God bless you, is a common English expression addressed to a person after they sneeze. The origin of the custom and its original purpose are unknown.

An alternative response to sneezing is the German word Gesundheit or Salud (meaning Health) in the Spanish language.

Several possible origins are commonly given. The practice of blessing someone who sneezes, dating as far back as at least AD 77, however, is far older than most specific explanations can account for.

One explanation holds that the custom originally began as an actual blessing. Gregory I became Pope in AD 590 as an outbreak of the bubonic plague was reaching Rome. In hopes of fighting off the disease, he ordered unending prayer and parades of chanters through the streets. At the time, sneezing was thought to be an early symptom of the plague. The blessing ("God bless you!") became a common effort to halt the disease.

A variant of the Pope Gregory I story places it with Pope Gregory VII, then tells the common story of "Ring Around the Rosey" being connected to the same plague.

John Winston Ono Lennon, MBE (9 October 1940 – 8 December 1980) was an English musician and singer-songwriter who rose to worldwide fame as one of the founder members of The Beatles, one of the most commercially successful and critically acclaimed acts in the history of popular music. Together with Paul McCartney, he formed one of the most celebrated songwriting partnerships of the 20th century.

Born and raised in Liverpool, Lennon became involved as a teenager in the skiffle craze; his first band, The Quarrymen, evolved into The Beatles in 1960. As the group disintegrated towards the end of the decade, Lennon embarked on a solo career that produced the critically acclaimed albums John Lennon/Plastic Ono Band and Imagine, and iconic songs such as "Give Peace a Chance" and "Imagine". After his marriage to Yoko Ono in 1969, he changed his name to John Ono Lennon. Lennon disengaged himself from the music business in 1975 to devote time to raising his infant son Sean, but re-emerged with Ono in 1980 with the new album Double Fantasy. He was murdered three weeks after its release.