TMC

TMC may stand for:

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TMC2

Transmembrane channel-like protein 2 is a protein that in humans is encoded by the TMC2 gene.

Function

This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, expression in the inner ear suggests that it may be crucial for normal auditory function.

Clinical significance

Mutations in this gene may underlie hereditary disorders of balance and hearing.

References

Further reading

TMC6

Transmembrane channel-like protein 6 is a protein that in humans is encoded by the TMC6 gene.In vivo, TMC6 and its homolog TMC8, interact and form a complex with the zinc transporter 1 (SLC30A1) and localize mostly to the endoplasmic reticulum, but also to the nuclear membrane and Golgi apparatus.

Inactivating mutations in TMC6 or TMC8 have been implicated as the genetic cause of the rare skin disorder epidermodysplasia verruciformis, which is characterized by abnormal susceptibility to human papillomaviruses (HPVs) of the skin resulting in the growth of scaly macules and papules, particularly on the hands and feet.

References

Further reading

Highway

A highway is any public road or other public way on land. It is used for major roads, but also includes other public roads and public tracks: It is not an equivalent term to freeway (motorway), or a translation for autobahn, autoroute, etc.

In North American and Australian English, major roads such as controlled-access highways or arterial roads are often state highways (Canada: provincial highways). Other roads may be designated "county highways" in the US and Ontario. These classifications refer to the level of government (state, provincial, county) that maintains the roadway.

In British English, "highway" is primarily a legal term. Everyday use normally implies roads, while the legal use covers any route or path with a public right of access, including footpaths etc.

The term has led to several related derived terms, including highway system, highway code, highway patrol and highwayman.

The term highway exists in distinction to "waterway".

Overview

Major highways are often named and numbered by the governments that typically develop and maintain them. Australia's Highway 1 is the longest national highway in the world at over 14,500 km or 9,000 mi and runs almost the entire way around the continent. China has the world's largest network of highways followed closely by the United States of America. Some highways, like the Pan-American Highway or the European routes, span multiple countries. Some major highway routes include ferry services, such as U.S. Route 10, which crosses Lake Michigan.

Highway (2014 Hindi film)

Highway is a 2014 Indian drama film written and directed by Imtiaz Ali and produced by Sajid Nadiadwala. The film stars Randeep Hooda and Alia Bhatt in the lead roles.The film narrates the story of a young woman who develops Stockholm syndrome. Screened in the Panorama section of the 2014 Berlin International Film Festival, the film released worldwide on 21 February 2014 The film is based on the episode of the same name from the Zee TV anthology series Rishtey, starring Aditya Srivastava and Kartika Rane,which was also written and directed by Imtiaz Ali.

Plot

The story begins on the eve of the wedding of Veera Tripathi (Alia Bhatt), the daughter of a rich business tycoon. She is at a Fuel Station by the highway with her fiancé when she is abducted. The gang who kidnaps her panics when they find out that her father has links in the government. However, Mahabir Bhati (Randeep Hooda), one of her abductors, is willing to do whatever it takes to see this through. They continuously move to different cities, to avoid being tracked by police. As the days go by, Veera finds peace and a new-found freedom in her bondage to the point that she confides in him of her troubled childhood. Her fear of abduction is taken over by a sense of freedom.

Highway (1995 film)

Highway is a 1995 Malayalam action thriller film directed by Jayaraaj, written by Sab John, story by Jayaraaj and produced by Prem Prakash.

Plot

This movie is a crime thriller. Suresh Gopi is a Research and Analysis Wing (RAW) officer who comes in disguise to a colony to investigate a bomb blast which killed 30 innocent college students. Bhanupriya falls in love with Suresh Gopi and the rest of the story revolves around how Suresh Gopi solves the case.

Cast

External links