The simplified molecular-input line-entry system or SMILES is a specification in form of a line notation for describing the structure of chemical molecules using short ASCII strings. SMILES strings can be imported by most molecule editors for conversion back into two-dimensional drawings or three-dimensional models of the molecules.

The original SMILES specification was developed by Arthur Weininger and David Weininger in the late 1980s. It has since been modified and extended by others, most notably by Daylight Chemical Information Systems Inc. In 2007, an open standard called "OpenSMILES" was developed by the Blue Obelisk open-source chemistry community. Other 'linear' notations include the Wiswesser Line Notation (WLN), ROSDAL and SLN (Tripos Inc).

In July 2006, the IUPAC introduced the InChI as a standard for formula representation. SMILES is generally considered to have the advantage of being slightly more human-readable than InChI; it also has a wide base of software support with extensive theoretical (e.g., graph theory) backing.

Judy Garland (June 10, 1922 – June 22, 1969) was an American actress, singer and vaudevillian. Renowned for her contralto voice, she attained international stardom through a career that spanned 45 of her 47 years as an actress in musical and dramatic roles, as a recording artist and on the concert stage. Respected for her versatility, she received a Juvenile Academy Award and won a Golden Globe Award, as well as Grammy Awards and a Special Tony Award. She was nominated for the Academy Award for Best Actress for her role in the remake of A Star is Born and for Best Supporting Actress for her performance in the 1961 film, Judgment at Nuremberg. At 39 years of age, she remains the youngest recipient of the Cecil B. DeMille Award for lifetime achievement in the motion picture industry.

After appearing in vaudeville with her two older sisters, Garland was signed to Metro-Goldwyn-Mayer as a teenager. There she made more than two dozen films, including nine with Mickey Rooney and the 1939 film with which she would be most identified, The Wizard of Oz. After 15 years, she was released from the studio but gained renewed success through record-breaking concert appearances, including a return to acting beginning with critically acclaimed performances.

Avril Ramona Lavigne (pronunciation: /ˈævrɨl ləˈviːn/; AV-ril lə-VEEN; born 27 September 1984) is a Canadian singer-songwriter. She was born in Belleville, Ontario, but spent most of her youth in the small town of Napanee. By the age of 15, she had appeared on stage with Shania Twain; by 16, she had signed a two-album recording contract with Arista Records worth more than $2 million. In 2002, when she was 17 years old, Lavigne broke onto the music scene with her debut album Let Go.

Let Go made Lavigne the youngest female soloist to reach No. 1 in the UK, and the album was certified four-times platinum by the Recording Industry Association of America. By 2009, over 16 million copies had been sold worldwide. Her breakthrough single, "Complicated", peaked at No. 1 in many countries around the world, as did the album Let Go. Her second album, Under My Skin, was released in 2004 and was her first album to peak at No. 1 on the U.S. Billboard 200, eventually selling more than 10 million copies worldwide. The Best Damn Thing, Lavigne’s third album, was released in 2007, becoming her third No. 1 album in the UK Albums Chart and featuring her first U.S. Billboard Hot 100 No. 1 single, "Girlfriend". Lavigne has scored six number-one singles worldwide, including "Complicated", "Sk8er Boi", "I'm with You", "My Happy Ending", "Nobody's Home", and "Girlfriend". With more than 30 million copies of her albums sold worldwide, Lavigne is one of the top-selling artists releasing albums in the U.S., with over 10.25 million copies certified by the RIAA. Her fourth studio album, Goodbye Lullaby, was released in March 2011. Goodbye Lullaby gave Lavigne her fourth top 10 album on the U.S. Billboard 200 and the UK Albums Chart and her third No. 1 album in both Japan and Australia. Three months after the release of Goodbye Lullaby, Lavigne began work on her fifth album, which will be released on Epic Records following her departure from RCA Records.