The Harlem River Drive is a north–south parkway in the New York City borough of Manhattan. It runs along the west bank of the Harlem River from the Triborough Bridge in East Harlem to 10th Avenue in Inwood, where the parkway continues north as Dyckman Street. The portion of the Harlem River Drive from the Triborough Bridge to the Alexander Hamilton Bridge is a limited-access highway. South of the Robert F. Kennedy Bridge, the parkway continues toward lower Manhattan as FDR Drive.

The parkway opened to traffic in 1964. In 2003, the New York State Department of Transportation ceremoniously designated the parkway as the "369th Harlem Hellfighters Drive" in honor of the all-black regiment that fought to defend France during World War I.

The Drive originated as the Harlem River Speedway, which attracted horse owners. Genteel carriages were permitted, but not sulkies and drays in the initial years. Later, car drivers could also race along the stretch of road. The dirt roadway stretched two and one-half miles from West 155th Street to West 208th Street.

Harlem is a neighborhood in the New York City borough of Manhattan, which since the 1920s has been a major African-American residential, cultural and business center. Originally a Dutch village, formally organized in 1658, it is named after the city of Haarlem in the Netherlands. Harlem was annexed to New York City in 1873.

Harlem has been defined by a series of boom-and-bust cycles, with significant ethnic shifts accompanying each cycle. Black residents began to arrive en masse in 1904, with numbers fed by the Great Migration. In the 1920s and 1930s, the neighborhood was the focus of the "Harlem Renaissance", an outpouring of artistic and professional works without precedent in the American black community. However, with job losses in the time of the Great Depression and the deindustrialization of New York City after World War II, rates of crime and poverty increased significantly.

New York's revival in the late 20th century has led to renewal in Harlem as well. By 1995, Harlem was experiencing social and economic gentrification. Though the percentage of residents who are black peaked in 1950, the area remains predominantly black.

The Harlem River is a navigable tidal strait in New York City, USA that flows 8 miles (13 km) between the Hudson River and the East River, separating the boroughs of Manhattan and the Bronx. Part of the current course of the Harlem River is the Harlem River Ship Canal, which runs somewhat south of the former course of the river, isolating a small portion of Manhattan (Marble Hill) on the Bronx side of the river.

The Harlem River is spanned by seven swing bridges, three lift bridges, and four arch bridges, and is navigable to any boat with less than 55 feet (16.8 m) of air draft. However, any boat requiring more than 5 feet (1.5 m) of clearance will require the Spuyten Duyvil Bridge to swing open. All other movable bridges on the Harlem River provide at least 24 feet (7.3 m) of clearance while closed, so boats and ships requiring between 5 and 24 feet (1.5 and 7.3 m) of clearance need only have one bridge swing open. These bridges replaced fixed bridges or lower bridges in the late 19th century to improve navigation. In recent years,^[when?] test openings of the movable bridges on the Harlem River have outnumbered openings for navigation. There are no fees for navigation of the river. High Bridge was erected between 1837 and 1848 to carry the Croton Aqueduct across the river. It is the oldest bridge in New York City.