A children's hospital is a hospital which offers its services exclusively to children (including teenagers). The number of children's hospitals proliferated in the 20th century, as pediatric medical and surgical specialties separated from internal medicine and adult surgical specialties. Children's hospitals are characterized by greater attention to the psychosocial support of children and their families.

In addition to the psychosocial support of children and families, Children's hospitals have the added benefit of being staffed by professionals who are trained in treating children. While many normal hospitals can treat children adequately, pediatric specialists may be a better choice when it comes to treating rare afflictions that may prove fatal or severely detrimental to young children, in some cases before birth. Also, many children's hospitals will continue to see children with rare illnesses into adulthood, allowing for a continuity of care.

Every year US News & World Report ranks the top children's hospitals and pediatric specialties in the United States. For the year 2010-2011, eight hospitals ranked in all 10 pediatric specialties. These hospitals make up the 2010-11 Best Children's Hospitals Honor Roll and are listed in alphabetical order as follows: