- published: 30 Jul 2016
- views: 1273
Angioedema, also known as angiooedema, Quincke's edema, and angioneurotic edema, is the rapid swelling (edema) of the dermis, subcutaneous tissue,mucosa and submucosal tissues. It is very similar to urticaria, but urticaria, commonly known as hives, occurs in the upper dermis.
Cases where angioedema progresses rapidly should be treated as a medical emergency, as airway obstruction and suffocation can occur. Epinephrine may be life-saving when the cause of angioedema is allergic. In the case of hereditary angioedema, treatment with epinephrine has not been shown to be helpful.
Angioedema is classified as either hereditary or acquired.
Acquired angioedema (AAE) can be immunologic, nonimmunologic, or idiopathic. It is usually caused by allergy and occurs together with other allergic symptoms and urticaria. It can also occur as a side effect to certain medications, particularly ACE inhibitors. It is characterized by repetitive episodes of swelling, frequently of the face, lips, tongue, limbs, and genitals. Edema of the gastrointestinal mucosa typically leads to severe abdominal pain; in the upper respiratory tract, it can be life-threatening.
Hereditary angioedema (HAE) is a rare, autosomal dominantly inherited blood disorder that causes episodic attacks of swelling that may affect the face, extremities, genitals, gastrointestinal tract and upper airways. In this form of angioedema, swellings of the intestinal mucous membrane may lead to vomiting and painful, colic-like intestinal spasms that may mimic intestinal obstruction. Airway edema may be life-threatening. Episodes may be triggered by trauma, surgery, dental work, menstruation, some medications, viral illness and stress; however, this is not always readily determined. This disorder affects approximately one in 10,000–50,000 people.
The underlying cause of most HAE is autosomal dominant inheritance of mutations in the C1 inhibitor gene (C1-INH gene or SERPING1 gene), which is mapped to chromosome 11 (11q12-q13.1).To date there are over 300 known genetic mutations that result in a deficiency of functional C1 inhibitor protein. The majority of HAE patients have a family history; however, 25% are the result of new mutations. The low level of C1 inhibitor in the plasma leads to increased activation of pathways that release bradykinin, the chemical responsible for the angioedema due to increased vascular permeability, and the pain seen in individuals with HAE.
One Of Patient, Doctor and Society (PDS) videos..! Angioedema is a skin condition very similar to hives. In hives, raised, red, itchy, irregular bumps appear on the skin; in angioedema, the same thing happens beneath the skin. Instead of being itchy, angioedema is tender or painful. This video offers additional details about this condition and how it develops.
Angioedema may be caused by an allergic reaction. During the reaction, histamine and other chemicals are released into the bloodstream. The body releases histamine when the immune system detects a foreign substance called an allergen. In most cases, the cause of angioedema is never found. The following may cause angioedema: Animal dander (scales of shed skin) Exposure to water, sunlight, cold or heat Foods (such as berries, shellfish, fish, nuts, eggs, and milk) Insect bites Medicines (drug allergy), such as antibiotics (penicillin and sulfa drugs), nonsteroidal anti-inflammatory drugs (NSAIDs), and blood pressure medicines (ACE inhibitors) Pollen
angioedema: what is it, how to treat it, medical treatment, follow up.
An overview of the approach to Angioedema in the ED, plus a discussion about some of the newer treatment modalities. Chris Maples and I gave this lecture to the Medical Staff at Sentara Obici Hospital on 2/10/15.
Hi guys, my name is MK. You can also find me on my website at http://myjourneytobefree.com If you are looking for Angioedema and Hives Treatment, please watch this video and visit my website. It has references to Angioedema and Urticaria Symptoms and a natural treatment for hives and Angioedema. In this video you can see my angioedema pictures I took a few years ago for my doctor. I was diagnosed with angioedema over ten years ago. I began to have symptoms right after I had my beautiful baby girl. And it was not until after struggling with angioedema outbreaks for a year that I finally decided to see a doctor. And then another doctor and another... From one allergist to another, with a lot of blood tests and all kinds of other allergy tests done over and over. But none of them could tel...
UC San Diego Health System, in partnership with U.S. Hereditary Angioedema Association, a non-profit patient advocacy organization, has opened the nation’s first dedicated center for diagnosing and treating diverse forms of swelling, known collectively as angioedema. For more information, please visit http://health.ucsd.edu/specialties/allergy/angioedema/Pages/default.aspx
It has been a long journey but I finally have an answer for all of the other random symptoms I have experienced the past few years that were unrelated to my other issues and allergies. I have been diagnosed with a rare genetic disorder called Hereditary Angioedema also known as HAE. It is a potentially life threatening disorder that can cause a wide array of symptoms, the primary being bad swelling in the GI tract, throat, skin, and extremities. I am very glad to have an answer finally, but I am having a difficult time coping with my diagnosis. I am sharing to update you all and to vent a little to try and cope with what's going on. If you are interested in finding anything out about my disorder, this is the link to the US support system for people with HAE. Now the people with the facia...
Read More-http://www.searchherbalremedy.com/top-natural-cures-for-angioedema/
Urticaria (from the Latin urtica, "nettle" from urere, "to burn"),[1] commonly referred to as hives, is a kind of skin rash notable for pale red, raised, itchy bumps. Hives may cause a burning or stinging sensation.[2] They are frequently caused by allergic reactions; however, there are many nonallergic causes. Most cases of hives lasting less than six weeks (acute urticaria) are the result of an allergic trigger. Chronic urticaria (hives lasting longer than six weeks) is rarely due to an allergy. The majority of chronic hives cases have an unknown (idiopathic) cause. In perhaps more than 50% of patients with chronic idiopathic urticaria, it is caused by an autoimmune reaction