Trudi Schupbach (Princeton Univ) Part 1 Axes formation in the Drosophila Egg
- Order:
- Duration: 22:05
- Published: 26 Mar 2010
- Uploaded: 09 Jun 2011
- Author: ibioseminars
How do complex multicellular organisms develop from single celled eggs with a single nucleus? We study this question in the fruit fly, Drosophila. In these insects, as in many other organisms, the major body plan is predetermined during oogenesis, or egg development. In the first part of the lecture, I will give an introduction to oogenesis in Drosophila, and the techniques we use to find genes that are responsible for determining the major axes of the egg and embryo. Interestingly, our analysis revealed that this process requires cell to cell communication between the oocyte and the surrounding follicle cells. It involves a signaling molecule, Gurken, which provides a localized signal from the oocyte to the follicle cells and ultimately sets up both the anterior-posterior as well as the dorso-ventral axis of the egg. See more at www.ibioseminars.org
http://wn.com/Trudi_Schupbach_Princeton_Univ_Part_1_Axes_formation_in_the_Drosophila_Egg