- published: 21 Aug 2012
- views: 863941
Alzheimer's disease (AD), also known in medical literature as Alzheimer disease, is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death. It was first described by German psychiatrist and neuropathologist Alois Alzheimer in 1906 and was named after him.
Most often, AD is diagnosed in people over 65 years of age, although the less-prevalent early-onset Alzheimer's can occur much earlier. In 2006, there were 26.6 million sufferers worldwide. Alzheimer's is predicted to affect 1 in 85 people globally by 2050.
Although Alzheimer's disease develops differently for every individual, there are many common symptoms. Early symptoms are often mistakenly thought to be 'age-related' concerns, or manifestations of stress. In the early stages, the most common symptom is difficulty in remembering recent events. When AD is suspected, the diagnosis is usually confirmed with tests that evaluate behaviour and thinking abilities, often followed by a brain scan if available.
Seth Rogen (pronounced /ˈroʊɡɪn/; born April 15, 1982) is a Canadian stand-up comedian, actor, producer, screenwriter, and voice artist. Rogen began his career doing stand-up comedy during his teen years, winning the Vancouver Amateur Comedy Contest in 1998. While still living in his native Vancouver, he landed a small part in Freaks and Geeks. Shortly after Rogen moved to Los Angeles for his role, Freaks and Geeks was canceled after one season due to poor ratings. He then got a part on the equally short-lived Undeclared, which also hired him as a staff writer.
After landing a job as a staff writer on the final season of Da Ali G Show, for which Rogen and the other writers received an Emmy nomination, he was guided by film producer Judd Apatow toward a film career. Rogen was cast in a major supporting role and credited as a co-producer in Apatow's directorial debut, The 40-Year-Old Virgin. After Rogen received critical praise for that performance, Universal Pictures agreed to cast him as the lead in Apatow's directorial feature films Knocked Up and Funny People. Rogen and his comedy partner Evan Goldberg co-wrote the films Superbad, Pineapple Express, and The Green Hornet. Rogen has done voice work for the films Horton Hears a Who!, Kung Fu Panda, Monsters vs. Aliens, and Paul. He married fellow screenwriter Lauren Miller in October 2011.