British scientists could treat or even cure cancer using a groundbreaking technique that finds and attacks the “Achilles’ heel” of tumours, they say. Research by University College London harnesses the body’s immune system to wipe out each cancer cell in a “potentially revolutionary” way. It promises to be effective against fast-mutating types of the disease, such as lung cancer, that have so far evaded most treatments. Scientists are hopeful that it will work on all cancers. Researchers involved in the latest breakthrough warned that the work was in its early stages and trials were needed before it could be used to treat patients. Charles Swanton, from the UCL Cancer Institute, said: “I will be disappointed if we haven’t treated a patient [in a trial] within two years.” About 160,000 people die from cancer each year in the UK, accounting for almost a
President Hollande has signalled that he is ready to move the border with Britain back to Dover, saying there will be “consequences” if Britain leaves the EU. In a helpful intervention for Downing Street, the French president said that he could not rule out ripping up an agreement that allows border checks to take place in Calais. No 10 had already warned that France would issue the threat should voters back Brexit in the referendum in June. A spokesman said that moving the border could lead to migrant settlements like the Jungle springing up in Kent almost overnight. Mr Hollande made his intervention as he stood next to David Cameron after talks in Amiens, northern France. “I don’t want to scare you, but I just want to say the truth,” he said. “There will be consequences if the United Kingdom is to leave the EU. “There will be consequences in many are
By the standards of the world’s great national anthems, it is considered a plodding dirge: endured rather than loved. It’s a long time since anyone charged into battle with their blood up after hearing God Save the Queen. Yet for all it lacks in power to inspire, the national anthem’s place in English sporting culture looked safer last night after the organisations that run the England rugby and football teams came out against moves to drop it. Both bodies have close links to the royal family. The Queen is patron of the Rugby Football Union and Prince Harry vice-patron, while Prince William is president of the Football Association. Toby Perkins, a Labour MP, is pushing for England to get its own anthem, such as Jerusalem, to sing at sporting events instead of God Save the Queen. Campaigners backing his bill, which is due to get a second reading in parliament today, have organised a choir
Perhaps it’s because his grandfather was a tax-dodging brothel owner
Your questions answered on tax, falling values and currency issues
A new exhibition sets out to look at the legacy of the Renaissance master
Syria’s ceasefire is fragile but it has already shown that the best hope for the war’s civilian victims is peace at home, not an uncertain fate as refugees
England’s teams and supporters should sing Jerusalem with gusto
An early version of Hamlet returns to the stage for Shakespeare’s quatercentenary
Mexicans have taken up the music of Morrissey, translating it, often with some difficulty given the cultural references, and adding their own rhythms
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Ben Macintyre: No wonder The Donald is evasive about his German roots when his dynasty began with Friedrich Drumpf, a tax-dodging brothel owner
Carol Midgley: I never loved having someone come in to scrub my U-bend but the real reason is that it occupied too much headspace
Patrick Minford: EU protectionism is projected to raise our cost of living by 8%, with higher prices going direct into our European partners’ pockets
Sathnam Sanghera: You may have heard that the average London home will be worth more than the GDP of Manchester by 2030
Donald Tusk’s words reveal the rising sense of panic in Brussels and Athens
Pyongyang’s latest show of defiance came as the UN imposed its toughest sanctions yet in response to the Communist state’s nuclear tests
The sister of the King of Spain remained silent other than to answer questions put by her lawyer before a panel of three judges in Palma de Mallorca
Asset management company raises eyebrows by naming chief executive as non-executive chairman after criticising similar moves by others
The company voluntary arrangement is the latest chapter in the colourful corporate history of BHS, which opened its first store in Brixton in 1928
Net lending to small and medium-sized businesses from high street banks that participate in the Funding for Lending Scheme stood at £0.6 billion
Nationwide said the average price of a home rose to £196,930 last month and the rate of home ownership is showing signs of stabilising
Sunderland manager shocked and repulsed by player’s conviction
The man behind plans to guarantee English football’s ‘big five’ a place in a revamped Champions League says there are “good arguments” for a closed system
Club are still third, still only six points off the top, but they certainly cannot afford to wilt again in the white heat of a north London derby, Oliver Kay writes
Marcus Roberts: The path ahead for Trump to the nomination now lies with the winner-takes-all states of the coming weekend and March 15
Caroline Hill: New chair of Young Labour vows to take fight to a governing party hell-bent on stitching up politics for its own benefit
Cheryl Gillan: If we vote to “leave” we will remain the world’s fifth largest economy on the doorstep of a group of countries that needs us economically
Natasha Clark : George Osborne had the last laugh at Treasury Questions when he attacked Labour on their policy advisors
Men’s pursuit team were narrowly beaten by the scintillating Australians
It took a training injury to Kyle Edmund, to ratify selection but he may have been in the mind of Leon Smith, the captain, all along, Barry Flatman writes
Beer-loving Andy Goode admits he looks nothing like a serious athlete but his return to rugby has been an incredible success, John Westerby writes
If Scotland leaves the Union, the first minister can’t keep coming cap in hand to London for arts funding
The latest round of Letters Live opens next week with Ian McKellen and Russell Brand are reading letters by famous folk in a new stage show
The V&A’s show of work by the Italian master and those inspired by him proves who’s best, says Rachel Campbell-Johnston
Now that computer programs guide our music choices, there is no room for bad taste — or perhaps our sense of who we are
Kate Muir and Kevin Maher discuss the latest Coen brothers release
Mad Max costume designer Jenny Beavan’s fashion fracas, Oscars pregnancy rumours and Ariana Grande’s doggy role-play
The writer Robert Jones’s Murder was an unconventionally told examination of grief as untreated sewage
Alice Holloway, a lingerie designer, is to name her latest underwear set after Amal Clooney: the Alamuddin collection, after the human rights lawyer’s maiden name
There’s an obvious next step for Schroders: renaming the whole thing Dobsons, in tribute to the chief executive now stepping up to chairman
Jeremy Corbyn is growing on me. There is something almost admirable about the way he refuses to behave like a normal politician
Young reporters are being challenged to write a 1,000 word essay on ‘journalism in the digital era’ to win a place at the International Journalism Festival
This city is moving on from industrial decline, says Ruth Bloomfield
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Art galleries, A-list restaurants and smart flats are turning Vauxhall, a supremely accessible part of the South Bank, into the new hip suburb in the capital
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