Khatri is a caste from the northern Indian subcontinent. Khatris in India are mostly from the Punjab region, but they later migrated to regions like Rajasthan, Uttar Pradesh, Delhi, Jammu, Uttarkhand, Himachal Pradesh, Gujarat, Madhya Pradesh, Haryana, Balochistan, Sindh and Khyber Pakhtunkhwa.

Khatris played an important role in India's transregional trade under the Mughal Empire. With the Mughal patronage, they adopted administrative and military roles outside the Punjab region as well. Scott Cameron Levi describes Khatris among the "most important merchant communities of early modern India."

All the Sikh Gurus were Khatris. The current Prime Minister of India, Dr. Manmohan Singh, is also a Khatri.

The word "Khatri" is believed by some to be the Punjabi adaptation of Sanskrit word Kshatriya, used to describe the warriors in the traditional Hindu varna system. However, a number of sources deny the connection of Khatri caste with ancient Kshatriya Hindu military order. According to one theory, the word "Khatri" originates from the word Khsatri mentioned in Manu Smriti to denote a mixed caste of low-ritual status, born of the union of Kshatriya mothers and Shudra fathers. Dasrath Sharma also described Khatris as a mixed pratiloma caste of low ritual status, but he suggested that Khatris could be a mixed caste born of Kshatriya fathers and Brahmin mothers.