The trigger for Alzheimer’s disease can be passed between people through contaminated surgical tools, a landmark study suggests. Until now, scientists believed that the disease was mostly a consequence of old age and partly influenced by genes. The new findings raise the prospect that patients could develop dementia as a result of a hospital operation, a blood transfusion or dental work such as root canal treatment. The study, published in Nature yesterday, is the first evidence that the “seeds” of Alzheimer’s — microscopic protein molecules — could be transmitted between humans. The discovery was described by the study’s lead scientist as a paradigm shift in the understanding of how Alzheimer’s develops. John Collinge, professor of neurology at University College London, said: “You could have three different ways you have these protein seeds generated in your brain. Either they happen spontaneously — an unlucky event as you age — or you have got a faulty gene or you’ve been exposed to a medical accident. That’s what we’re hypothesising. It’s a paradigm shift.” More than 500,000 people in the UK live with Alzheimer’s, which accounts for just under two thirds of dementia cases. It is thought to kill 40,000 people a year and to cost the economy about £16 billion. The team found no evidence that Alzheimer’s itself was contagious but said that medical procedures could result in protein build-ups that presage the disea
The pilot of a British Airways plane engulfed by flames on a Las Vegas runway has been praised for his calm and brave response as disaster struck on what was due to be the penultimate flight of his 42-year career. Chris Henkey, 63, has been identified as the pilot at the controls of a stricken Boeing 777-200, whose engine burst into flames with 170 people on board during take-off en route to Gatwick. He managed to abort the take-off of flight 2276 in just nine seconds before the jet became airborne at McCarran international airport. Within five minutes, all passengers and crew were evacuated via emergency chutes. The blaze, which was hot enough to melt some of the plane’s windows, was put out by around 50 firefighters. A total of 14 people were treated for minor injuries at a nearby hospital in America’s gambling capital, including Mr Henkey, who was checked for smoke inhalation. All hav
British taxpayers face a £90 million bill to relocate 160,000 asylum seekers between European countries in a scheme that David Cameron said could encourage more people to risk their lives travelling to the continent. The prime minister has repeatedly said that Britain had opted out of emergency compulsory quotas that will distribute refugees around EU nations. The scheme was formally announced yesterday by Jean-Claude Juncker, the European Commission president. Downing Street said last night, however, that British taxpayers would still end up footing part of the bill. Britain is exempted because of longstanding European treaty opt-outs from EU asylum policy, but the government is required to pay the bills. The refugees chosen for “relocation” will be from Syria, Afghanistan and Eritrea and countries taking them will receive €6,000 per person. Hungary, Greece and Italy will be paid €500
United is not yet a club in crisis, but senior players are expressing frustration
Nixon let property tycoon know in 1987 that he’d spotted his potential
Catwalks of Paris may be a source of funds for jihad as terrorists seize land
The Juncker plan for Europe to take 160,000 refugees is in fact a plan to take an unlimited number of people for an unlimited time
Parents know the best time for summer-born children to start school
Labour may soon have cause to regret the departure of its moderate interim leader
Charlotte Proudman has accused a solicitor of ‘disgusting sexism’ after he sent her a message on the networking site LinkedIn calling her ‘stunning’
Defence Equipment and Support (DE&S), Abbey Wood, Bristol and Corsham, £36,562 (pay award pending)
Gentoo, United Kingdom
The Coventry Building Society, Coventry, West Midlands, Competitive
100s of Graduate Jobs & Schemes. Start your Search Here
Lamborghini Aventador LP 700-4 Roadster Grigio Estoque with nero marrone leather
1965 Ferrari I 250 TR recreation red with leather
Bentley Continental GT V8 glacier white with beluga hide
Aston Martin Vanquish 2+2 volcano red with winter wheat leather
Located at 21 East 61st Street, The Carlton House is the most prestigious address to call home
Magnificent 1-5 Bedroom Residences on Manhattan’s Upper West Side
Salcombe’s first development of new properties right on the water’s edge for almost twenty years.
Discover the ultimate global address in New York, designed by Foster + Partners
7 nts B&B in Luxury Boutique, Ngala Lodge. Includes flights, transfers & romantic package
Spectacular views, spa facilities, fine dining...relax, we’re offering more nights for free
When staying at the 4* db San Antonio Hotel & spa, Malta this summer
Save £500pp on 2016 European cruises inc meals, selected drinks, tips & excursions.
Jenni Russell: Trump, Clinton and Corbyn show it’s not older people’s ability that has held them back but our prejudice about what they can do
Janice Turner: The stalwarts will still canvass under Corbyn. Whereas the Corbynistas, if their guy doesn’t win, will drift back to the Greens or Russell Brand
Kevin Toolis: The collapse of Ulster’s power-sharing executive shortly before an election is a perfect storm that could sweep Gerry Adams to power in Dublin
Simon Nixon: The eurosceptics can keep their fingers crossed that the current migration crisis will succeed where the euro crisis has so far failed
Satellite pictures show Russian military cargo planes arriving at a Syrian airfield
Dharampal Singh said he had recordings of village elders vowing revenge upon the girls after their brother eloped with a higher-caste woman
China has spent billions of yuan to boost the material lives of people in Tibet, which has had double-digit economic growth for 20 years
Ofcom has opened an official investigation under the Communications Act into BT’s excuses when it fails to connect lines in time
Mark Carney, the governor of the Bank of England, may be Britain’s most powerful unelected official but he can be undermined by his colleagues
Manufacturing output contracted by 0.8 per cent between June and July as demand faltered from the slowdown gripping emerging markets
Stock markets in Asia and Europe rallied yesterday after China promised to introduce additional measures to kick-start growth
The squad has become exasperated by the stifling methods of the Dutchman
Dutchman says fees for players are routinely overblown in this ‘crazy world’, but the France striker was bought with next United manager in mind
Oliver Kay says captain’s feat of becoming England’s leading goalscorer is superb, but, as a player, he does not compare to Sir Bobby Charlton
Philip Webster: the prime minister has suggested waiting for the election of the new Labour leader before tabling another Commons motion
Bruno Waterfield: PM’s decision to take 20,000 Syrian refugees – 4,000 annually – over the next five years is a snub to his European partners
John McTernan: I believe there was a legal case, the deeper problem however is the logical rather than the legal basis for the drone strike
Britain’s response to the refugee crisis is not helping David Cameron and George Osborne in securing any referendum concessions from the EU
British athlete’s long-term physio Gerard Hartmann says former athlete is clean
The World Cup winner likes the Bath fly half and England’s World Cup chances, but is acutely aware that the media can make unhelpful demands
It might not have had the Greatest Day but it did prove the Greatest Date for music lovers and rugby supporters at the O2, Alyson Rudd writes
George Osborne’s praise of Bob Geldof’s line ‘give us all your effin money’ was marred only slightly by his thanking Bob Dylan
If there is time to consult the attorney-general, there is time to seek the approval of a judicial authority, says Lord Pannick, QC
The weekly appearance of the PM in the Commons affords MPs a chance to remind him of those who desperately need a break in this cruel world
If anyone is going to ease the acute housing shortage in the next few years, it is the biggest half dozen housebuilding companies
Jenny Rowe, chief executive of the Supreme Court, reflects on her career
Ministers will face increasing calls to adopt US-style openness when launching future drone strikes, legal experts predicted
A team project where risks and rewards are shared may be the future of ligation, says Edward Fennell
If you plant this stunning array of colourful bulbs this autumn and your garden and window boxes will burst into life next spring
Let Bill Bailey, Richard E Grant and Celia Imrie bring children’s classic ‘The Jungle Book - The Mowgli Stories’ to life in our latest free audiobook
Join us for an exclusive event with the Northern Ballet as they give us a sneak peek at their creative process and their new production of 1984
We’ll be whisking one lucky winner and a guest away to stay in a glamorous hotel a short distance from Dubrovnik’s magnificently preserved old city
Join free to meet thousands of other like-minded readers
Providing a secure, simple and efficient way of making international currency transfers while saving you money in the process
Purchase your favourite prints from our famed cartoonists, as well as famous and popular photographs from The Times Archive