Mon May 23 2016: Two Naldemedine Phase III Studies Show Consistent Improvement Of Opioid-Induced Constipation (Shionogi Inc)

Edit Public Technologies 23 May 2016
COMPOSE I and COMPOSE II found that, for the primary endpoint*, 47.6 percent and 52.5 percent of patients taking 0.2 mg tablet of naldemedine experienced improvements in the frequency of spontaneous bowel movements (SBMs) for at least nine out of the 12 weeks, compared with 34.6 percent and 33.6 percent of patients on placebo, respectively ... 1.8 percent on placebo; in COMPOSE II, it was 5.2 vs....

Despite Pressing Need, Survey Finds Most Americans Unlikely to Enroll in Clinical Trials (Memorial Sloan-Kettering Cancer Center)

Edit Public Technologies 23 May 2016
Worry over side effects / safety (55 percent) Uncertainty about insurance and out-of-pocket costs (50 percent) Inconvenience of trial locations (48 percent) Concerns about getting a placebo (46 percent) Skeptical of a treatment that is not yet proven to work (35 percent) Worries over feeling like 'guinea pigs' (34 percent) ... 'For example, the vast majority of clinical trials do not involve a placebo.'....

Winship participates in global study to test new drug in breast cancer patients (The Winship Cancer Institute of Emory University)

Edit Public Technologies 23 May 2016
(Source. The Winship Cancer Institute of Emory University) ... The OlympiA clinical study is a randomized, double-blind, placebo-controlled phase III study investigating whether adjuvant olaparib can reduce the risk of breast cancer recurrence after standard therapy in patients with BRCA1 or BRCA2 mutations. Patients will be given either olaparib or placebo for 12 months ... Learn more about clinical trials at Winship ... Pictured ... (noodl....

Bardoxolone Methyl (RTA 402) Data Show Improvement in Renal Function by Inulin Clearance in a Phase 2 Clinical Study in Japan(17KB) (Kyowa Hakko Kirin Co Ltd)

Edit Public Technologies 23 May 2016
The clinical study is a randomized, double-blind*2, parallel group, placebo-controlled study in patients with chronic kidney disease (CKD) and type II diabetes, and has been evaluating the safety and efficacy of once-daily administration of RTA 402 for 16 weeks ... significant improvement in GFR was seen in the RTA 402 compared with the placebo group....

Crystal meth made cold medicine rubbish

Edit New Scientist 23 May 2016
To crack down on criminal chemists, many cold medicines have had their active ingredient removed, now many are potentially no better than placebos ... ....

Why Relypsa (RYLP) Stock Is Surging Today

Edit The Street 23 May 2016
Also, daily administration resulted in a dose-related decrease in urine sodium compared to the placebo that was given out, the Redwood ......

CHAMPIX® (varenicline) European Union Label Updated to Include New Safety and Efficacy Data from the ...

Edit Stockhouse 23 May 2016
EAGLES is a post-authorization safety study/post-marketing requirement study, which was conducted in 16 countries and designed to evaluate the neuropsychiatric safety of CHANTIX/CHAMPIX and bupropion versus placebo and nicotine replacement therapy patch (NRT) in patients with and without a history of psychiatric disorder ... a double-blind, randomized, placebo-controlled clinical trial....

CHAMPIX® (varenicline) European Union Label Updated to Include New Safety and Efficacy Data from the EAGLES Clinical Trial Following Endorsement from CHMP (Pfizer Inc)

Edit Public Technologies 23 May 2016
EAGLES is a post-authorization safety study/post-marketing requirement study, which was conducted in 16 countries and designed to evaluate the neuropsychiatric safety of CHANTIX/CHAMPIX and bupropion versus placebo and nicotine replacement therapy patch (NRT) in patients with and without a history of psychiatric disorder ... a double-blind, randomized, placebo-controlled clinical trial....

Synthetic Biologics Announces Detailed Data from Two SYN-010 Phase 2 Clinical Trials for the Treatment of Irritable Bowel Syndrome with Constipation (IBS-C) (Synthetic Biologics Inc)

Edit Public Technologies 23 May 2016
The two SYN-010 Phase 2 clinical trials are comprised of a randomized, double-blind, placebo-controlled, 4-week study comparing SYN-010 21 mg and 42 mg dose strengths to placebo (Study 1), followed by an open-label study in which eligible patients who completed Study 1 received SYN-010 42 mg for an additional 8 weeks (Study 2) ... Placebo / SYN-010 42 mg ... Placebo / SYN-010 42 mg....

City of Inverness Pipe Band are British Champions (Highland Council)

Edit Public Technologies 23 May 2016
On their second competitive outing, the newly established City of Inverness Pipe Band has won the grade 4A category of the prestigious British Pipe Band Championships held on Saturday 21 May 2016 at James Park, Paisley. Around 4,000 pipers and drummers performed at Paisley and the City of Inverness Pipe Band were jubilant at winning the grade 4A ... The City of Inverness Pipe Band is supported by the Inverness Common Good Fund....

Pansy Division celebrates turning 25 by kicking out the jams

Edit The Miami Herald 23 May 2016
With a loyal cult following that goes back to the dawn of the 1990s, the groundbreaking openly gay band Pansy Division celebrates its 25th anniversary this year. The group was a pioneer in the "queercore" scene, a movement of out gay and lesbian musicians that included such other post-punk bands as Fifth Column and Tribe 8 ... "Joel is not gay, so the band is three-quarters gay," Ginoli says....

Zac Brown Band Performs For Record-Breaking Crowd (Shore Fire Media Inc)

Edit Public Technologies 23 May 2016
Zac Brown Band broke attendance records last night performing for 25,227 concert goers at Camden's BB&T; Pavilion on their 'BLACK OUT THE SUN' tour ... The band has made a habit of breaking records ... Zac Brown Band's 'BLACK OUT THE SUN' tour continues through the summer and will return to the tri-state area for a special ocean-side performance in Atlantic City Beach on September 1st ... 1, the band has sold over eight million albums to date....

band contests are a blast (Tameside Metropolitan Borough Council)

Edit Public Technologies 23 May 2016
THOUSANDS of music lovers defied the weather to watch dozens of bands compete in the ever popular Whit Friday band contests. Ashton-under-Lyne Band excelled, finishing third in the open section ... Mossley claimed the local championship, finishing ahead of Stalybridge Old Band and St John's, Mossley ... However, the evening was not only about senior bands....
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