Hypothyroidism

AKC Canine Health Foundation Launches Hypothyroidism Research Focus

Hypothyroidism is a condition caused by a deficiency in the hormones produced by the thyroid gland. The most common symptoms of hypothyroidism are weight gain, intolerance to cold, lethargy, skin problems such as hair loss and infections, and reproductive and nervous system abnormalities. Thyroid hormones influence most of the dog’s body systems, and thyroid deficiency causes a decreased metabolic rate.  Decreased metabolic rate can lead to decreased body temperature, weight gain, decreased heart rate and decreased mental function. 

Hypothyroidism is believed to be the most common endocrine disorder in dogs.  Any breed of dog and mixed-breeds can be affected by hypothyroidism, but some breeds are believed to be predisposed to the condition.  The causes of hypothyroidism include inflammation (thyroiditis) or progressive failure (atrophy) of the thyroid glands. In rare cases, thyroid tumors may cause hypothyroidism.

Hypothyroidism Research Focus Sponsors

Lead Sponsors ($25,000+)

Treeing Walker Breeders & Fanciers Association

Sponsors ($2,500+)

American Shih Tzu Club, Inc.
Great Pyrenees Club of America
Tibetan Terrier Club of America/Tibetan Terrier Health & Welfare Foundation

Thanks to the the support of the organizations listed above, a hypothyroidism grant has been awarded!

Phase I of this effort is officially underway, but we still need your support for the next phase of this important research!

Hypothyroidism research is an unmet need articulated by dog clubs, owners and veterinarians. We can make a real difference and deliver a tangible outcome for hypothyroidism.

Hypothyroidism remains difficult to diagnose in the dog. It is consensus opinion in the veterinary community that hypothyroidism is over-diagnosed.  Effective treatment of clinical symptoms relies on effective diagnostic tools.

This research focus seeks to identify a biomarker panel that will lead to the accurate diagnosis of canine hypothyroidism. Once accurate diagnostic tools are developed, CHF intends to support research that will identify risk factors for the development of hypothyroidism in the dog, with the goal being to empower breeders to make informed breeding decisions.

For more information about the impact of our hypothyroidism research focus see the request for proposals released to the research community.

Additional Hypothyroidism Resources

Hypothyroidism in Dogs from the American College of Veterinary Internal Medicine

Thyroid testing and breed statistics from the Orthopedic Foundation for Animals