CFH

CFH may refer to:

Factor H

Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at typical concentrations of 200–300 micrograms per milliliter). Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3-convertase, C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses, because it binds to glycosaminoglycans (GAGs) that are generally present on host cells but not, normally, on pathogen surfaces.

Structure and function

Royal Alexandra Hospital, Edmonton

The Royal Alexandra Hospital (RAH) is a large and long serving hospital in the Canadian province of Alberta. Operated by Alberta Health Services and located in the Edmonton's city centre, the Royal Alexandra serves a diverse community stretching from downtown Edmonton to western and northern Canada.

They operate 678 beds, and care for 450,000 patients annually. The RAH is home to the Women's Health Centre, the Regional Eye Centre and the Aboriginal Health program, in addition to a wide range of child, adult and geriatric programs and services.

History

The Royal Alexandra Hospital is named after Queen Alexandra (1844-1925), consort of King Edward VII, the King of Canada from 1901 to 1910. It was granted the "Royal" prefix by Edward in 1907.

References