Samé

Samé or Samé Diomgoma is a village and commune in the Cercle of Kayes in the Kayes Region of south-western Mali. The commune includes 18 villages and lies to the south of the Senegal River. The Dakar-Niger Railway passes through Samé. In 2009 the commune had a population of 12,820.

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Sam (horse)

Sam (1815 – after 1827) was a British Thoroughbred racehorse and sire. In a career that lasted from April 1818 to May 1819 he ran nine times and won three races. In May 1818 he defeated fifteen opponents to record his most important win in the Epsom Derby. His only other wins came in a walkover and a match race. After running without success as a four-year-old, Sam was retired to stud but made no impact as a sire of winners.

Background

Sam was described as a "low, lengthy and plain sort of horse, with a sour countenance, and a delicate constitution," sired by the Doncaster Cup winner Scud out of the mare Hyale. Hyale produced several other winners and was a half-sister to Goosander, a highly successful broodmare who produced the Epsom Oaks winner Shoveler and the Derby winner Sailor. Sam was bred by his owner, Thomas Thornhill at his stud at Riddlesworth, Norfolk, and trained by Thornhill's father-in-law, Mr Perren.

Sam was named after his regular jockey Sam Chifney, Jr. Chifney was one of the outstanding jockeys of his era, and one of the first to hold horses up in the early stages of a race before finishing strongly: he became famous for this tactic which became known as the "Chifney Rush". He eventually became the joint-trainer of the colt that bore his name.

Spynet

Spynet is a CBC Television children's show, which features Sam, played by Kim Schraner, as a spy operative for a fictional Canadian spy agency, the National Espionage Task-Force (NET). It started as an ultra-low budget segment, of short length, but increased modestly in budget and length, to a half hour format. It aired on February 25, 2002 to 2004 and is directed by Michael Kinney

The episodes, built to be educational with a plot, vary in their content-action ratio.

Show format

Originally, the show had only one visible regular, known under her code name of Sam. However, as the budget and length of the show increased, a number of recurring characters appeared, although the focus is still heavily on Sam. Sam works in a white, windowless van parked in an anonymous city, which she hops around, trying to stop crime. The van is filled with lots of high-tech spy gadgets and computer equipment. The show is mainly filmed in downtown Toronto, and makes great use of the CBC's extensive, private building, which many of the scenes are filmed in.±

TAP2

TAP2 is a gene in humans that encodes the protein Antigen peptide transporter 2.

Function

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2 (TAP1). The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, schizophrenia, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.

TAP Portugal Flight 425

TAP Flight 425 was a regular flight from Brussels, Belgium, to Madeira Airport (informally known as Funchal Airport), Portugal, with an intermediate scheduled stop in Lisbon. On November 19, 1977, the Boeing 727 operating the service overran Madeira Airport's runway before crashing onto the nearby beach and exploding, killing 131 of the 164 people on board. It remains TAP's only fatal accident in its history.

Aircraft

The aircraft operating flight TP-425 was a Boeing 727-282 Advanced registration CS-TBR named after the Portuguese aviation pioneer Sacadura Cabral. Its manufacturer serial number was 20972/1096 and was delivered to TAP on 21 January 1975. It was powered by 3 Pratt & Whitney JT8D-17 turbofan engines which had a maximum thrust of 16,000 lbf each. The aircraft had completed a B check on 21 September 1977, and at the time of the accident had accumulated 6,154 flying hours in 5,204 cycles.

Accident

Shortly before 9:48pm on that Saturday evening, after 13 hours and 15 minutes of service time, the tired crew of the 727 was trying to land the airplane on the difficult Madeira airport runway, which at the time was 1,600 m (5,250 ft) long. After two unsuccessful attempts to land the aircraft, the Captain João Lontrão and Co-pilot Miguel Guimarães Leal decided to make one last try to land the plane, before they would have to make the decision to divert to the Gran Canaria Airport in the Canary Islands.

TAP1

Transporter associated with Antigen Processing 1 is a protein that in humans is encoded by the TAP1 gene.

Function

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.

See also

Interactions

TAP1 has been shown to interact with:

References

Den (newspaper)

Den (Ukrainian: День, The Day) is a Kiev-based, centrist daily broadsheet newspaper.

History and profile

Den was founded in 1996. The paper is linked to former prime minister Yevhen Marchuk, his wife Larysa Ivshyna is the paper's editor-in-chief. Den has been supporting NATO and ties with the West.

The paper is also notable by its annual photography contest, being the main photo event in Ukraine.

Den is a member of UAPP.

References

External links