Heinrich Hermann Robert Koch ([ˈkɔx]; 11 December 1843 – 27 May 1910) was a German physician. He became famous for isolating Bacillus anthracis (1877), the Tuberculosis bacillus (1882) and Vibrio cholerae (1883) and for his development of Koch's postulates.
He was awarded the Nobel Prize in Physiology or Medicine in 1905 for his tuberculosis findings. He is considered one of the founders of microbiology, inspiring such major figures as Paul Ehrlich and Gerhard Domagk.
Koch was born in Clausthal in the Harz Mountains, then part of Prussia, as the son of a mining official. He studied medicine under Friedrich Gustav Jakob Henle at the University of Göttingen and graduated in 1866. He then served in the Franco-Prussian War and later became district medical officer in Wollstein (Wolsztyn), Prussian Poland. Working with very limited resources, he became one of the founders of bacteriology, the other major figure being Louis Pasteur.
After Casimir Davaine demonstrated the direct transmission of the anthrax bacillus between cows, Koch studied anthrax more closely. He invented methods to purify the bacillus from blood samples and grow pure cultures. He found that, while it could not survive outside a host for long, anthrax built persisting endospores that could last a long time.