Cell therapy

Cell therapy (also called cellular therapy or cytotherapy) is therapy in which cellular material is injected into a patient; this generally means intact, living cells. For example, T cells capable of fighting cancer cells via cell-mediated immunity may be injected in the course of immunotherapy.

Cell therapy originated in the nineteenth century when scientists experimented by injecting animal material in an attempt to prevent and treat illness. Although such attempts produced no positive benefit, further research found in the mid twentieth century that human cells could be used to help prevent the human body rejecting transplanted organs, leading in time to successful bone marrow transplantation.

Today two distinct categories of cell therapy are recognized.

The first category is cell therapy in mainstream medicine. This is the subject of intense research and the basis of potential therapeutic benefit. Such research can be controversial when it involves human embryonic material.

Cell Therapy

"Cell Therapy" is the debut single by the Goodie Mob, released as the lead single from their debut album, Soul Food. Fellow Dungeon Family members Organized Noize produced the song.

The song became a top-40 hit, peaking at number 39 on the Billboard Hot 100 while also topping the Billboard Hot Rap Singles at number one. To date it remains the group's only single to reach the top-40.

The song has also appeared on Goodie Mob's greatest hits compilation Dirty South Classics and Cee Lo Green's Closet Freak: The Best of Cee-Lo Green the Soul Machine.

Single track listing

A-Side

B-Side

Chart history

Peak positions

Year-end charts

References

External links

Goodie Mob

Goodie Mob is a hip-hop group based in Atlanta, Georgia that formed in 1991 and currently consists of members Cee-Lo, Khujo, T-Mo, and Big Gipp.

History

The group's name acts as a double backronym. As explained on the track "Fighting" on Soul Food, Goodie Mob means "the GOOD DIE Mostly Over Bullshit".

All four members were born in Atlanta, and the group is based there with the rest of the Dungeon Family, a collective that includes OutKast and P.A. (Parental Advisory). Goodie was first heard featured on several songs from OutKast's first album Southernplayalisticadillacmuzik.

All four members had a feature cameo in the 1999 film, "Mystery Men" as a criminal gang known as The Not-So-Goodie-Mob.

Cee-Lo was the most visible member of the group prior to his departure in 2000 (among other projects, he was recording in collaboration with DJ Danger Mouse as Gnarls Barkley), while Big Gipp has made several rounds on other Dungeon Family members' albums, and T-Mo and Khujo form a duo within the group called The Lumberjacks.

Stem-cell therapy

Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition.

Bone marrow transplant is the most widely used stem-cell therapy, but some therapies derived from umbilical cord blood are also in use. Research is underway to develop various sources for stem cells, and to apply stem-cell treatments for neurodegenerative diseases and conditions, diabetes, heart disease, and other conditions.

With the ability of scientists to isolate and culture embryonic stem cells, and with scientists' growing ability to create stem cells using somatic cell nuclear transfer and techniques to create induced pluripotent stem cells, controversy has crept in, both related to abortion politics and to human cloning. Additionally, efforts to market treatments based on transplant of stored umbilical cord blood have been controversial.

Medical uses

For over 30 years, bone marrow has been used to treat cancer patients with conditions such as leukaemia and lymphoma; this is the only form of stem-cell therapy that is widely practiced. During chemotherapy, most growing cells are killed by the cytotoxic agents. These agents, however, cannot discriminate between the leukaemia or neoplastic cells, and the hematopoietic stem cells within the bone marrow. It is this side effect of conventional chemotherapy strategies that the stem-cell transplant attempts to reverse; a donor's healthy bone marrow reintroduces functional stem cells to replace the cells lost in the host's body during treatment. The transplanted cells also generate an immune response that helps to kill off the cancer cells; this process can go too far, however, leading to graft vs host disease, the most serious side effect of this treatment.

Cell

Cell(s) may refer to:

Science and technology