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Although any dog can be tested for DM, it is possible that the genetic background that predominates in some breeds prevents the development of symptoms even in dogs testing affected (at risk). At this time we are reluctant to recommend testing for members of breeds where the University of Missouri has not yet proven susceptibility to DM through microscopic examination of spinal cords from deceased dogs that exhibited symptoms of the disease. At this time the required evidence of association between the genetic mutation and actual spinal cord evaluations has only been proven in the breeds listed: