- published: 26 Feb 2015
- views: 8406
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Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime.
But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%.
Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it?
Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below.
SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS
http://www.youtube.com/user/drjayharness
VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS
http://www.breastcanceranswers.com/news
SUBMIT A QUESTION
http://www.breastcanceranswers.com/
DOWNLOAD DR. HARNESS' 15 QUESTIONS TO ASK YOUR DOCTOR
http://www.breastcanceranswers.com/
CONNECT WITH US!
Google+: http://bit.ly/16nhEnr
Facebook: https://www.facebook.com/BreastCancerAnswers
Twitter: https://twitter.com/BreastCancerDr
Michelle found out she has a gene which gives her high chances of breast and ovarian cancer, meets women with similar issues and talks to Lorraine about it with Dr Hilary Jones
- published: 11 Oct 2012
- views: 14637
www.elarasystems.com
October is breast cancer awareness month, and while most people are aware of breast cancer, they may be unaware of certain factors which increase the risk of developing the disease.
Individuals with a strong family history of breast cancer may choose to receive a gene test to assess these risks.
A gene test looks for specific mutations in your BRCA1 or BRCA2 gene. A mutation in these genes can be inherited from either your mother or your father.
BRCA1 and BRCA2 help control normal cell growth. Mutations in these genes may increase the risk of developing breast cancer.
According to the National Cancer Institute:
About 12% of women in the general population will develop breast cancer. However, about 45% of women who have inherited a BRCA2 mutation will develop breast cancer, and about 55-65% of women with a BRCA1 mutations will develop breast cancer.
Consider putting together an early detection plan and be proactive about your health.
- published: 14 Oct 2014
- views: 5051
http://www.ovarian-cancer-facts.com/
This nicely animated 2 minute video shows how hereditary BRCA1 and BRCA2 gene mutations can increase the risk of cancer.
It provides a good overview of how the genes work and how they protect the body from disease.
http://www.ovarian-cancer-facts.com/
Keywords for this video are:
BRCA1
BRCA1 Gene
BRCA2
BRCA2 Gene
BRCA1 and cancer
BRCA1 and BRCA2
BRCA2 and Cancer
Gene Mutation
Cancer
Ovarian Cancer
- published: 08 Nov 2009
- views: 22719
EXPLORE THE RI ADVENT CALENDAR: http://rigb.org.uk/advent
Mistakes in the "recipe" of your DNA -- if bits of code go missing, or get swapped or damaged -- could spell the difference between life and death. DNA often gets damaged by everyday processes within our bodies, but also from external factors such as UV radiation or tobacco smoke. Luckily, our bodies are well equipped to fix this damage thanks, in part, to the BRCA2 gene, found on chromosome 13.
BRCA2 encodes for a large protein which carries out repair work on damaged DNA. It's no surprise then that if the BRCA2 is faulty, or missing, our cells can't repair themselves properly. As a result, the damaged DNA builds up and this can lead to cancer.
In turns out, however, that faults on BRCA2 aren't necessarily such an advantage to cancer cells. As their BRCA2 gene is faulty, the only remaining "tool" in a cancer cell's molecular repair kit is another gene known as PARP. Dr Kat Arney from Cancer Research UK explains how by using drugs to block PARP function, scientists are hoping to prevent cancer cells from repairing themselves, causing them to die off. Whilst developing cancer treatments is certainly no piece of cake, drugs with PARP inhibitors are already showing great promise in trials.
You can find out more about research into PARP inhibitors on the Cancer Research UK science blog at the following links:
http://scienceblog.cancerresearchuk.org/2008/07/10/a-%E2%80%98lethal-weapon%E2%80%99-in-the-search-for-new-cancer-treatments/
http://scienceblog.cancerresearchuk.org/2011/07/12/widening-the-net-for-parp-inhibitors/
For more information on related cancer research visit: www.cruk.org
With thanks to BBSRC: http://bbsrc.ac.uk/
Don't miss the 2013 CHRISTMAS LECTURES on BBC Four, BBC iPlayer and the Ri Channel: http://rigb.org/christmas-lectures
The Ri is on Twitter: http://twitter.com/ri_science
and Facebook: http://www.facebook.com/royalinstitution
Subscribe for the latest science videos: http://richannel.org/newsletter
- published: 13 Dec 2013
- views: 15152
We aired a story a few weeks ago about the BRCA mutation, and breast cancer. Sarah Parker saw that story and wrote into the Viewers’ Voice.
- published: 27 Sep 2014
- views: 389
Because harmful BRCA1 and BRCA2 gene mutations are relatively rare in the general population, most experts agree that mutation testing of individuals who do not have cancer should be performed only when the person’s family history suggests the possible presence of a harmful mutation in BRCA1 or BRCA2.
There are options for Couples with known BRCA 1 and BRCA 2 genes: PGD is one of them.
- published: 11 Sep 2014
- views: 2108
BRCA2
BRCA2 and BRCA2 (/ˌbrækəˈtuː/) are a human gene and its protein product, respectively. The official symbol (BRCA2, italic for the gene, nonitalic for the protein) and the official name (breast cancer 2) are maintained by the HGNC. Orthologs, styled Brca2 and Brca2, are common in other mammal species.BRCA2 is a human tumor suppressor gene (specifically, a caretaker gene), found in all humans; its protein, also called by the synonym breast cancer type 2 susceptibility protein, is responsible for repairing DNA.
BRCA2 and BRCA1 are normally expressed in the cells of breast and other tissue, where they help repair damaged DNA or destroy cells if DNA cannot be repaired. They are involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this increases the risk for breast cancer. Thus, although the terms "breast cancer susceptibility gene" and "breast cancer susceptibility protein" (used frequently both in and outside the medical literature) sound as if they describe a proto-oncogene or oncogene, BRCA1 and BRCA2 are "normal"; it is their mutation that is abnormal.
This page contains text from Wikipedia, the Free Encyclopedia -
https://wn.com/BRCA2
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
This article is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License, which means that you can copy and modify it as long as the entire work (including additions) remains under this license.
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2:20What is BRCA1 and BRCA2?
What is BRCA1 and BRCA2?What is BRCA1 and BRCA2?
Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime. But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%. Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it? Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below. SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS http://www.youtube.com/user/drjayharness VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS http://www.breastcanceranswers.com/news SUBMIT A QUESTION http://www.breastcanceranswers.com/ DOWNLOAD DR. HARNESS' 15 QUESTIONS TO ASK YOUR DOCTOR http://www.breastcanceranswers.com/ CONNECT WITH US! Google+: http://bit.ly/16nhEnr Facebook: https://www.facebook.com/BreastCancerAnswers Twitter: https://twitter.com/BreastCancerDr -
7:39Michelle Heaton having cancer gene BRCA2 interview - Lorraine 9th October 2012
Michelle Heaton having cancer gene BRCA2 interview - Lorraine 9th October 2012Michelle Heaton having cancer gene BRCA2 interview - Lorraine 9th October 2012
Michelle found out she has a gene which gives her high chances of breast and ovarian cancer, meets women with similar issues and talks to Lorraine about it with Dr Hilary Jones -
4:39BRCA2 at 22
BRCA2 at 22 -
1:16Breast Cancer BRCA1 & BRCA2 Gene Mutations HD
Breast Cancer BRCA1 & BRCA2 Gene Mutations HDBreast Cancer BRCA1 & BRCA2 Gene Mutations HD
www.elarasystems.com October is breast cancer awareness month, and while most people are aware of breast cancer, they may be unaware of certain factors which increase the risk of developing the disease. Individuals with a strong family history of breast cancer may choose to receive a gene test to assess these risks. A gene test looks for specific mutations in your BRCA1 or BRCA2 gene. A mutation in these genes can be inherited from either your mother or your father. BRCA1 and BRCA2 help control normal cell growth. Mutations in these genes may increase the risk of developing breast cancer. According to the National Cancer Institute: About 12% of women in the general population will develop breast cancer. However, about 45% of women who have inherited a BRCA2 mutation will develop breast cancer, and about 55-65% of women with a BRCA1 mutations will develop breast cancer. Consider putting together an early detection plan and be proactive about your health. -
2:09BRCA1 and BRCA2 Hereditary Gene Mutation and Cancer
BRCA1 and BRCA2 Hereditary Gene Mutation and CancerBRCA1 and BRCA2 Hereditary Gene Mutation and Cancer
http://www.ovarian-cancer-facts.com/ This nicely animated 2 minute video shows how hereditary BRCA1 and BRCA2 gene mutations can increase the risk of cancer. It provides a good overview of how the genes work and how they protect the body from disease. http://www.ovarian-cancer-facts.com/ Keywords for this video are: BRCA1 BRCA1 Gene BRCA2 BRCA2 Gene BRCA1 and cancer BRCA1 and BRCA2 BRCA2 and Cancer Gene Mutation Cancer Ovarian Cancer -
2:155 days post preventative double mastectomy. BRCA2 positive.
5 days post preventative double mastectomy. BRCA2 positive.5 days post preventative double mastectomy. BRCA2 positive.
5 days post preventative double mastectomy. BRCA2 positive. -
4:14Chromosome 13 - BRCA2 and DNA Damage
Chromosome 13 - BRCA2 and DNA DamageChromosome 13 - BRCA2 and DNA Damage
EXPLORE THE RI ADVENT CALENDAR: http://rigb.org.uk/advent Mistakes in the "recipe" of your DNA -- if bits of code go missing, or get swapped or damaged -- could spell the difference between life and death. DNA often gets damaged by everyday processes within our bodies, but also from external factors such as UV radiation or tobacco smoke. Luckily, our bodies are well equipped to fix this damage thanks, in part, to the BRCA2 gene, found on chromosome 13. BRCA2 encodes for a large protein which carries out repair work on damaged DNA. It's no surprise then that if the BRCA2 is faulty, or missing, our cells can't repair themselves properly. As a result, the damaged DNA builds up and this can lead to cancer. In turns out, however, that faults on BRCA2 aren't necessarily such an advantage to cancer cells. As their BRCA2 gene is faulty, the only remaining "tool" in a cancer cell's molecular repair kit is another gene known as PARP. Dr Kat Arney from Cancer Research UK explains how by using drugs to block PARP function, scientists are hoping to prevent cancer cells from repairing themselves, causing them to die off. Whilst developing cancer treatments is certainly no piece of cake, drugs with PARP inhibitors are already showing great promise in trials. You can find out more about research into PARP inhibitors on the Cancer Research UK science blog at the following links: http://scienceblog.cancerresearchuk.org/2008/07/10/a-%E2%80%98lethal-weapon%E2%80%99-in-the-search-for-new-cancer-treatments/ http://scienceblog.cancerresearchuk.org/2011/07/12/widening-the-net-for-parp-inhibitors/ For more information on related cancer research visit: www.cruk.org With thanks to BBSRC: http://bbsrc.ac.uk/ Don't miss the 2013 CHRISTMAS LECTURES on BBC Four, BBC iPlayer and the Ri Channel: http://rigb.org/christmas-lectures The Ri is on Twitter: http://twitter.com/ri_science and Facebook: http://www.facebook.com/royalinstitution Subscribe for the latest science videos: http://richannel.org/newsletter -
4:55Sarah Parker talks testing positive for BRCA2
Sarah Parker talks testing positive for BRCA2Sarah Parker talks testing positive for BRCA2
We aired a story a few weeks ago about the BRCA mutation, and breast cancer. Sarah Parker saw that story and wrote into the Viewers’ Voice. -
5:50The Three B's; BRCA1, BRCA2, and Breast Cancer
The Three B's; BRCA1, BRCA2, and Breast Cancer -
5:20CACRM - BRCA1 and BRCA2: Cancer Risk and Genetic Testing
CACRM - BRCA1 and BRCA2: Cancer Risk and Genetic TestingCACRM - BRCA1 and BRCA2: Cancer Risk and Genetic Testing
Because harmful BRCA1 and BRCA2 gene mutations are relatively rare in the general population, most experts agree that mutation testing of individuals who do not have cancer should be performed only when the person’s family history suggests the possible presence of a harmful mutation in BRCA1 or BRCA2. There are options for Couples with known BRCA 1 and BRCA 2 genes: PGD is one of them.
-
What is BRCA1 and BRCA2?
Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime. But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%. Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it? Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below. SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS http://www.youtube.com/user/drjayharness VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS http://www.breastcanceranswers.com/news SUBMIT A QUESTION http://www.b...
published: 26 Feb 2015 -
Michelle Heaton having cancer gene BRCA2 interview - Lorraine 9th October 2012
Michelle found out she has a gene which gives her high chances of breast and ovarian cancer, meets women with similar issues and talks to Lorraine about it with Dr Hilary Jones
published: 11 Oct 2012 -
-
Breast Cancer BRCA1 & BRCA2 Gene Mutations HD
www.elarasystems.com October is breast cancer awareness month, and while most people are aware of breast cancer, they may be unaware of certain factors which increase the risk of developing the disease. Individuals with a strong family history of breast cancer may choose to receive a gene test to assess these risks. A gene test looks for specific mutations in your BRCA1 or BRCA2 gene. A mutation in these genes can be inherited from either your mother or your father. BRCA1 and BRCA2 help control normal cell growth. Mutations in these genes may increase the risk of developing breast cancer. According to the National Cancer Institute: About 12% of women in the general population will develop breast cancer. However, about 45% of women who have inherited a BRCA2 mutation will develop breast...
published: 14 Oct 2014 -
BRCA1 and BRCA2 Hereditary Gene Mutation and Cancer
http://www.ovarian-cancer-facts.com/ This nicely animated 2 minute video shows how hereditary BRCA1 and BRCA2 gene mutations can increase the risk of cancer. It provides a good overview of how the genes work and how they protect the body from disease. http://www.ovarian-cancer-facts.com/ Keywords for this video are: BRCA1 BRCA1 Gene BRCA2 BRCA2 Gene BRCA1 and cancer BRCA1 and BRCA2 BRCA2 and Cancer Gene Mutation Cancer Ovarian Cancer
published: 08 Nov 2009 -
5 days post preventative double mastectomy. BRCA2 positive.
5 days post preventative double mastectomy. BRCA2 positive.
published: 12 Aug 2015 -
Chromosome 13 - BRCA2 and DNA Damage
EXPLORE THE RI ADVENT CALENDAR: http://rigb.org.uk/advent Mistakes in the "recipe" of your DNA -- if bits of code go missing, or get swapped or damaged -- could spell the difference between life and death. DNA often gets damaged by everyday processes within our bodies, but also from external factors such as UV radiation or tobacco smoke. Luckily, our bodies are well equipped to fix this damage thanks, in part, to the BRCA2 gene, found on chromosome 13. BRCA2 encodes for a large protein which carries out repair work on damaged DNA. It's no surprise then that if the BRCA2 is faulty, or missing, our cells can't repair themselves properly. As a result, the damaged DNA builds up and this can lead to cancer. In turns out, however, that faults on BRCA2 aren't necessarily such an advantage to c...
published: 13 Dec 2013 -
Sarah Parker talks testing positive for BRCA2
We aired a story a few weeks ago about the BRCA mutation, and breast cancer. Sarah Parker saw that story and wrote into the Viewers’ Voice.
published: 27 Sep 2014 -
-
CACRM - BRCA1 and BRCA2: Cancer Risk and Genetic Testing
Because harmful BRCA1 and BRCA2 gene mutations are relatively rare in the general population, most experts agree that mutation testing of individuals who do not have cancer should be performed only when the person’s family history suggests the possible presence of a harmful mutation in BRCA1 or BRCA2. There are options for Couples with known BRCA 1 and BRCA 2 genes: PGD is one of them.
published: 11 Sep 2014
What is BRCA1 and BRCA2?
- Order: Reorder
- Duration: 2:20
- Updated: 26 Feb 2015
- views: 8406
Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetim...
Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime.
But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%.
Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it?
Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below.
SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS
http://www.youtube.com/user/drjayharness
VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS
http://www.breastcanceranswers.com/news
SUBMIT A QUESTION
http://www.breastcanceranswers.com/
DOWNLOAD DR. HARNESS' 15 QUESTIONS TO ASK YOUR DOCTOR
http://www.breastcanceranswers.com/
CONNECT WITH US!
Google+: http://bit.ly/16nhEnr
Facebook: https://www.facebook.com/BreastCancerAnswers
Twitter: https://twitter.com/BreastCancerDr
wn.com/What Is Brca1 And Brca2
Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene mutation, have only a 12% chance of getting breast cancer in their lifetime.
But, women with BRCA1 have about a 65% chance of developing it by the time they turn 70; the likelihood is a little lower for women with BRCA2 at 45%.
Now that you know how important BRCA1 & BRCA2 is and how it affects your cancer risk, what exactly is it?
Scottsdale Healthcare’s Gynecologic Oncologist Dr. Mike Janicek explains what BRCA1 & BRCA2 is in the video below.
SUBSCRIBE FOR MORE EXPERT INFORMATION AND BREAKING BREAST CANCER NEWS
http://www.youtube.com/user/drjayharness
VISIT BREASTCANCERANSWERS.com FOR THE LATEST IN BREAKING BREAST CANCER NEWS
http://www.breastcanceranswers.com/news
SUBMIT A QUESTION
http://www.breastcanceranswers.com/
DOWNLOAD DR. HARNESS' 15 QUESTIONS TO ASK YOUR DOCTOR
http://www.breastcanceranswers.com/
CONNECT WITH US!
Google+: http://bit.ly/16nhEnr
Facebook: https://www.facebook.com/BreastCancerAnswers
Twitter: https://twitter.com/BreastCancerDr
- published: 26 Feb 2015
- views: 8406
Michelle Heaton having cancer gene BRCA2 interview - Lorraine 9th October 2012
- Order: Reorder
- Duration: 7:39
- Updated: 11 Oct 2012
- views: 14637
Michelle found out she has a gene which gives her high chances of breast and ovarian cancer, meets women with similar issues and talks to Lorraine about it with...
Michelle found out she has a gene which gives her high chances of breast and ovarian cancer, meets women with similar issues and talks to Lorraine about it with Dr Hilary Jones
wn.com/Michelle Heaton Having Cancer Gene Brca2 Interview Lorraine 9Th October 2012
Michelle found out she has a gene which gives her high chances of breast and ovarian cancer, meets women with similar issues and talks to Lorraine about it with Dr Hilary Jones
- published: 11 Oct 2012
- views: 14637
BRCA2 at 22
- Order: Reorder
- Duration: 4:39
- Updated: 29 Jan 2014
- views: 495
First video post about my experience dealing with BRCA2 & a bilateral prophylactic mastectomy with reconstruction.
Here's my blog (where I update more regularl...
First video post about my experience dealing with BRCA2 & a bilateral prophylactic mastectomy with reconstruction.
Here's my blog (where I update more regularly): http://katmerwin.wordpress.com/
wn.com/Brca2 At 22
Breast Cancer BRCA1 & BRCA2 Gene Mutations HD
- Order: Reorder
- Duration: 1:16
- Updated: 14 Oct 2014
- views: 5051
www.elarasystems.com
October is breast cancer awareness month, and while most people are aware of breast cancer, they may be unaware of certain factors which in...
www.elarasystems.com
October is breast cancer awareness month, and while most people are aware of breast cancer, they may be unaware of certain factors which increase the risk of developing the disease.
Individuals with a strong family history of breast cancer may choose to receive a gene test to assess these risks.
A gene test looks for specific mutations in your BRCA1 or BRCA2 gene. A mutation in these genes can be inherited from either your mother or your father.
BRCA1 and BRCA2 help control normal cell growth. Mutations in these genes may increase the risk of developing breast cancer.
According to the National Cancer Institute:
About 12% of women in the general population will develop breast cancer. However, about 45% of women who have inherited a BRCA2 mutation will develop breast cancer, and about 55-65% of women with a BRCA1 mutations will develop breast cancer.
Consider putting together an early detection plan and be proactive about your health.
wn.com/Breast Cancer Brca1 Brca2 Gene Mutations Hd
www.elarasystems.com
October is breast cancer awareness month, and while most people are aware of breast cancer, they may be unaware of certain factors which increase the risk of developing the disease.
Individuals with a strong family history of breast cancer may choose to receive a gene test to assess these risks.
A gene test looks for specific mutations in your BRCA1 or BRCA2 gene. A mutation in these genes can be inherited from either your mother or your father.
BRCA1 and BRCA2 help control normal cell growth. Mutations in these genes may increase the risk of developing breast cancer.
According to the National Cancer Institute:
About 12% of women in the general population will develop breast cancer. However, about 45% of women who have inherited a BRCA2 mutation will develop breast cancer, and about 55-65% of women with a BRCA1 mutations will develop breast cancer.
Consider putting together an early detection plan and be proactive about your health.
- published: 14 Oct 2014
- views: 5051
BRCA1 and BRCA2 Hereditary Gene Mutation and Cancer
- Order: Reorder
- Duration: 2:09
- Updated: 08 Nov 2009
- views: 22719
http://www.ovarian-cancer-facts.com/
This nicely animated 2 minute video shows how hereditary BRCA1 and BRCA2 gene mutations can increase the risk of cancer....
http://www.ovarian-cancer-facts.com/
This nicely animated 2 minute video shows how hereditary BRCA1 and BRCA2 gene mutations can increase the risk of cancer.
It provides a good overview of how the genes work and how they protect the body from disease.
http://www.ovarian-cancer-facts.com/
Keywords for this video are:
BRCA1
BRCA1 Gene
BRCA2
BRCA2 Gene
BRCA1 and cancer
BRCA1 and BRCA2
BRCA2 and Cancer
Gene Mutation
Cancer
Ovarian Cancer
wn.com/Brca1 And Brca2 Hereditary Gene Mutation And Cancer
http://www.ovarian-cancer-facts.com/
This nicely animated 2 minute video shows how hereditary BRCA1 and BRCA2 gene mutations can increase the risk of cancer.
It provides a good overview of how the genes work and how they protect the body from disease.
http://www.ovarian-cancer-facts.com/
Keywords for this video are:
BRCA1
BRCA1 Gene
BRCA2
BRCA2 Gene
BRCA1 and cancer
BRCA1 and BRCA2
BRCA2 and Cancer
Gene Mutation
Cancer
Ovarian Cancer
- published: 08 Nov 2009
- views: 22719
5 days post preventative double mastectomy. BRCA2 positive.
- Order: Reorder
- Duration: 2:15
- Updated: 12 Aug 2015
- views: 230
5 days post preventative double mastectomy. BRCA2 positive.
5 days post preventative double mastectomy. BRCA2 positive.
wn.com/5 Days Post Preventative Double Mastectomy. Brca2 Positive.
Chromosome 13 - BRCA2 and DNA Damage
- Order: Reorder
- Duration: 4:14
- Updated: 13 Dec 2013
- views: 15152
EXPLORE THE RI ADVENT CALENDAR: http://rigb.org.uk/advent
Mistakes in the "recipe" of your DNA -- if bits of code go missing, or get swapped or damaged -- coul...
EXPLORE THE RI ADVENT CALENDAR: http://rigb.org.uk/advent
Mistakes in the "recipe" of your DNA -- if bits of code go missing, or get swapped or damaged -- could spell the difference between life and death. DNA often gets damaged by everyday processes within our bodies, but also from external factors such as UV radiation or tobacco smoke. Luckily, our bodies are well equipped to fix this damage thanks, in part, to the BRCA2 gene, found on chromosome 13.
BRCA2 encodes for a large protein which carries out repair work on damaged DNA. It's no surprise then that if the BRCA2 is faulty, or missing, our cells can't repair themselves properly. As a result, the damaged DNA builds up and this can lead to cancer.
In turns out, however, that faults on BRCA2 aren't necessarily such an advantage to cancer cells. As their BRCA2 gene is faulty, the only remaining "tool" in a cancer cell's molecular repair kit is another gene known as PARP. Dr Kat Arney from Cancer Research UK explains how by using drugs to block PARP function, scientists are hoping to prevent cancer cells from repairing themselves, causing them to die off. Whilst developing cancer treatments is certainly no piece of cake, drugs with PARP inhibitors are already showing great promise in trials.
You can find out more about research into PARP inhibitors on the Cancer Research UK science blog at the following links:
http://scienceblog.cancerresearchuk.org/2008/07/10/a-%E2%80%98lethal-weapon%E2%80%99-in-the-search-for-new-cancer-treatments/
http://scienceblog.cancerresearchuk.org/2011/07/12/widening-the-net-for-parp-inhibitors/
For more information on related cancer research visit: www.cruk.org
With thanks to BBSRC: http://bbsrc.ac.uk/
Don't miss the 2013 CHRISTMAS LECTURES on BBC Four, BBC iPlayer and the Ri Channel: http://rigb.org/christmas-lectures
The Ri is on Twitter: http://twitter.com/ri_science
and Facebook: http://www.facebook.com/royalinstitution
Subscribe for the latest science videos: http://richannel.org/newsletter
wn.com/Chromosome 13 Brca2 And Dna Damage
EXPLORE THE RI ADVENT CALENDAR: http://rigb.org.uk/advent
Mistakes in the "recipe" of your DNA -- if bits of code go missing, or get swapped or damaged -- could spell the difference between life and death. DNA often gets damaged by everyday processes within our bodies, but also from external factors such as UV radiation or tobacco smoke. Luckily, our bodies are well equipped to fix this damage thanks, in part, to the BRCA2 gene, found on chromosome 13.
BRCA2 encodes for a large protein which carries out repair work on damaged DNA. It's no surprise then that if the BRCA2 is faulty, or missing, our cells can't repair themselves properly. As a result, the damaged DNA builds up and this can lead to cancer.
In turns out, however, that faults on BRCA2 aren't necessarily such an advantage to cancer cells. As their BRCA2 gene is faulty, the only remaining "tool" in a cancer cell's molecular repair kit is another gene known as PARP. Dr Kat Arney from Cancer Research UK explains how by using drugs to block PARP function, scientists are hoping to prevent cancer cells from repairing themselves, causing them to die off. Whilst developing cancer treatments is certainly no piece of cake, drugs with PARP inhibitors are already showing great promise in trials.
You can find out more about research into PARP inhibitors on the Cancer Research UK science blog at the following links:
http://scienceblog.cancerresearchuk.org/2008/07/10/a-%E2%80%98lethal-weapon%E2%80%99-in-the-search-for-new-cancer-treatments/
http://scienceblog.cancerresearchuk.org/2011/07/12/widening-the-net-for-parp-inhibitors/
For more information on related cancer research visit: www.cruk.org
With thanks to BBSRC: http://bbsrc.ac.uk/
Don't miss the 2013 CHRISTMAS LECTURES on BBC Four, BBC iPlayer and the Ri Channel: http://rigb.org/christmas-lectures
The Ri is on Twitter: http://twitter.com/ri_science
and Facebook: http://www.facebook.com/royalinstitution
Subscribe for the latest science videos: http://richannel.org/newsletter
- published: 13 Dec 2013
- views: 15152
Sarah Parker talks testing positive for BRCA2
- Order: Reorder
- Duration: 4:55
- Updated: 27 Sep 2014
- views: 389
We aired a story a few weeks ago about the BRCA mutation, and breast cancer. Sarah Parker saw that story and wrote into the Viewers’ Voice.
We aired a story a few weeks ago about the BRCA mutation, and breast cancer. Sarah Parker saw that story and wrote into the Viewers’ Voice.
wn.com/Sarah Parker Talks Testing Positive For Brca2
We aired a story a few weeks ago about the BRCA mutation, and breast cancer. Sarah Parker saw that story and wrote into the Viewers’ Voice.
- published: 27 Sep 2014
- views: 389
The Three B's; BRCA1, BRCA2, and Breast Cancer
- Order: Reorder
- Duration: 5:50
- Updated: 21 Apr 2014
- views: 4129
A multimedia project for the 2014 Student Bio Expo by Rachael Sise. Exploring the definition of cancer, how breast cancer risks increase, genetic heredity, and ...
A multimedia project for the 2014 Student Bio Expo by Rachael Sise. Exploring the definition of cancer, how breast cancer risks increase, genetic heredity, and mutations of BRCA1 and BRCA2.
wn.com/The Three B's Brca1, Brca2, And Breast Cancer
CACRM - BRCA1 and BRCA2: Cancer Risk and Genetic Testing
- Order: Reorder
- Duration: 5:20
- Updated: 11 Sep 2014
- views: 2108
Because harmful BRCA1 and BRCA2 gene mutations are relatively rare in the general population, most experts agree that mutation testing of individuals who do not...
Because harmful BRCA1 and BRCA2 gene mutations are relatively rare in the general population, most experts agree that mutation testing of individuals who do not have cancer should be performed only when the person’s family history suggests the possible presence of a harmful mutation in BRCA1 or BRCA2.
There are options for Couples with known BRCA 1 and BRCA 2 genes: PGD is one of them.
wn.com/Cacrm Brca1 And Brca2 Cancer Risk And Genetic Testing
Because harmful BRCA1 and BRCA2 gene mutations are relatively rare in the general population, most experts agree that mutation testing of individuals who do not have cancer should be performed only when the person’s family history suggests the possible presence of a harmful mutation in BRCA1 or BRCA2.
There are options for Couples with known BRCA 1 and BRCA 2 genes: PGD is one of them.
- published: 11 Sep 2014
- views: 2108
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2:20
What is BRCA1 and BRCA2?
Women who have no family history of breast cancer and don’t carry the BRCA1 or 2 gene muta...
published: 26 Feb 2015
What is BRCA1 and BRCA2?
What is BRCA1 and BRCA2?
- Report rights infringement
- published: 26 Feb 2015
- views: 8406
7:39
Michelle Heaton having cancer gene BRCA2 interview - Lorraine 9th October 2012
Michelle found out she has a gene which gives her high chances of breast and ovarian cance...
published: 11 Oct 2012
Michelle Heaton having cancer gene BRCA2 interview - Lorraine 9th October 2012
Michelle Heaton having cancer gene BRCA2 interview - Lorraine 9th October 2012
- Report rights infringement
- published: 11 Oct 2012
- views: 14637
4:39
BRCA2 at 22
First video post about my experience dealing with BRCA2 & a bilateral prophylactic mastect...
published: 29 Jan 2014
BRCA2 at 22
BRCA2 at 22
- Report rights infringement
- published: 29 Jan 2014
- views: 495
1:16
Breast Cancer BRCA1 & BRCA2 Gene Mutations HD
www.elarasystems.com
October is breast cancer awareness month, and while most people are a...
published: 14 Oct 2014
Breast Cancer BRCA1 & BRCA2 Gene Mutations HD
Breast Cancer BRCA1 & BRCA2 Gene Mutations HD
- Report rights infringement
- published: 14 Oct 2014
- views: 5051
2:09
BRCA1 and BRCA2 Hereditary Gene Mutation and Cancer
http://www.ovarian-cancer-facts.com/
This nicely animated 2 minute video shows how here...
published: 08 Nov 2009
BRCA1 and BRCA2 Hereditary Gene Mutation and Cancer
BRCA1 and BRCA2 Hereditary Gene Mutation and Cancer
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- published: 08 Nov 2009
- views: 22719
2:15
5 days post preventative double mastectomy. BRCA2 positive.
5 days post preventative double mastectomy. BRCA2 positive.
published: 12 Aug 2015
5 days post preventative double mastectomy. BRCA2 positive.
5 days post preventative double mastectomy. BRCA2 positive.
- Report rights infringement
- published: 12 Aug 2015
- views: 230
4:14
Chromosome 13 - BRCA2 and DNA Damage
EXPLORE THE RI ADVENT CALENDAR: http://rigb.org.uk/advent
Mistakes in the "recipe" of you...
published: 13 Dec 2013
Chromosome 13 - BRCA2 and DNA Damage
Chromosome 13 - BRCA2 and DNA Damage
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- published: 13 Dec 2013
- views: 15152
4:55
Sarah Parker talks testing positive for BRCA2
We aired a story a few weeks ago about the BRCA mutation, and breast cancer. Sarah Parker ...
published: 27 Sep 2014
Sarah Parker talks testing positive for BRCA2
Sarah Parker talks testing positive for BRCA2
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- published: 27 Sep 2014
- views: 389
5:50
The Three B's; BRCA1, BRCA2, and Breast Cancer
A multimedia project for the 2014 Student Bio Expo by Rachael Sise. Exploring the definiti...
published: 21 Apr 2014
The Three B's; BRCA1, BRCA2, and Breast Cancer
The Three B's; BRCA1, BRCA2, and Breast Cancer
- Report rights infringement
- published: 21 Apr 2014
- views: 4129
5:20
CACRM - BRCA1 and BRCA2: Cancer Risk and Genetic Testing
Because harmful BRCA1 and BRCA2 gene mutations are relatively rare in the general populati...
published: 11 Sep 2014
CACRM - BRCA1 and BRCA2: Cancer Risk and Genetic Testing
CACRM - BRCA1 and BRCA2: Cancer Risk and Genetic Testing
- Report rights infringement
- published: 11 Sep 2014
- views: 2108
What is BRCA1 and BRCA2?...
Michelle Heaton having cancer gene BRCA2 interview...
BRCA2 at 22...
Breast Cancer BRCA1 & BRCA2 Gene Mutations HD...
BRCA1 and BRCA2 Hereditary Gene Mutation and Cance...
5 days post preventative double mastectomy. BRCA2...
Chromosome 13 - BRCA2 and DNA Damage...
Sarah Parker talks testing positive for BRCA2...
The Three B's; BRCA1, BRCA2, and Breast Cancer...
CACRM - BRCA1 and BRCA2: Cancer Risk and Genetic T...
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Lyrics list:lyrics
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Your Latest Victim, Park
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Too Far From North Shore, Park
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This Would Be Easier If You Would Just Die, Park
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Racing A Train, Park
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Numerous Murders, Park
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If You Could Concentrate, Park
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Gasoline Kisses for Everyone, Park
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Dear Sweet Impaler, Park
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Arcee Springer, Park
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Hide And Seek, Park
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Your Latest Victim
Throw me hard so I hit the concrete,
Scream words that you never did mean.
Even I can't stand this evidence,
It's clear, so clear.
Ringing in my ears won't stop,
And you've been smiling all along
(Burnt out!)
(Words are weakening)
She's in it for the nicotine, boys.
More poise than perfect,
Not worth saving, only leaving.
Break me up so my heart is shattered,
Three words that you never did mean.
Even I can't stand this evidence,
It's clear, so clear.
Ringing in my ears won't stop,
And you've been laughing all along.
(Burnt out!)
(Words are weakening)
She's in it for the nicotine, boys.
More poise than perfect,
Not worth saving, only leaving.
I can sit in this room and breathe abused,
I can do without the warmth from you.
But your knifelike smile needs a victim,
Worth your while.
(Words are weakening)
She's in it for the nicotine, boys.
More poise than perfect,
Not worth saving, only leaving.
(A lonely victim)
I can do what stab wounds never do,
I can peal the skin back just for you, beautiful you.
back
Donald Trump: We'll keep parts of Obamacare
Edit The Oklahoman 12 Nov 2016
President-elect Donald Trump appeared open Friday to compromising on his oft-repeated pledge to repeal and replace Obamacare -- citing a conversation with none other than President Barack Obama himself. But the openness was complicated by a shift in the official positions listed on his website ... Trump told the paper he was reconsidering his stance after Thursday's meeting with Obama, who urged him to protect parts of the law ... "No ... ....
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Prof. Predicted Trump’s Win, Predicts Impeachment (Video)
Edit Opposing Views 12 Nov 2016
Washington D.C.-based professor Allan Lichtman predicted that Republican presidential nominee Donald Trump would win the presidency, but he also believes that President-elect Trump will be impeached by his own party (video below) ... I'm going to make another prediction. This one is not based on a system; it's just my gut. If Donald Trump wins, I predict the Republicans in Congress will impeach him ... He's unpredictable ... So stay tuned ... ....
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Mysterious Unidentified Object Crashes in Myanmar
Edit Yahoo Daily News 12 Nov 2016
A large, unidentified metal object fell from the sky yesterday (Nov. 10) in the remote mountainous region of Myanmar. The cylindrical object, which is about 12 feet (3.7 meters) long and 5 feet in diameter, blasted into the village of Lone Khin, near a jade mine. Villagers woke early in the morning to a loud boom and vibrations, when the object fell to the ground ... "Initially, we thought it was a battle ... ....
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Donald Trump's victory averted World War Three, top Putin aide claims
Edit The Independent 11 Nov 2016
One of Vladimir Putin’s closest advisors has claimed Donald Trump’s victory has averted a third world war ... He told Russian news wire RNS....
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More than 900 migrants rescued at sea within hours
Edit CNN 12 Nov 2016
(CNN)More than 900 migrants were rescued from boats in the Mediterranean in the space of only a few hours Saturday morning, according to the humanitarian organization Doctors Without Borders, or Medecins Sans Frontieres. The group said via Twitter that 797 people -- including 205 women and 22 children -- were now on its ship, the Argos. More than 700 were rescued from a large wooden boat spotted before dawn ... #Update ... Read More ... ....
A counterintuitive approach to fighting cancer (University of Cambridge)
Edit Public Technologies 10 Nov 2016
(Source. University of Cambridge). If you're based at the Wellcome Trust/Cancer Research UK Gurdon Institute, however, the common sense approach is not necessarily the road most travelled - and for good reason ... However, this process also takes time ... In some cancer cells - most notably those associated with mutations in the BRCA1 or BRCA2 genes - this mechanism fails ... 'This was a 'Eureka' moment,' says Jackson ... stop cell death ... (noodl....
SURVIVOR’S MESSAGE:Be your own best advocate
Edit Palm Beach Post 09 Nov 2016
1 in 8 women will be diagnosed with breast cancer ... Breast cancer ranks second (after lung cancer) as a cause of cancer death in women An estimated 5 to 10 percent of breast cancer cases result from inherited mutations, including those in the breast cancer susceptibility genes BRCA1 and BRCA2 ... Women with BRCA2 mutations are estimated to have a 31 to 56 percent risk for developing breast cancer by age 70. Sources ... On Dec ... ....
Breast Cancer Screening & Prevention for Georgia Women (State of Georgia)
Edit Public Technologies 08 Nov 2016
(Source. State of Georgia). If you've been around for any amount of time, you've undoubtedly been affected by cancer - whether it's been you, a family member or a friend. If you haven't felt its ill effects, count yourself blessed ... Every day, over 120 Georgians continue to be diagnosed with some form of cancer ... Breast Cancer Prevention ... A majority of HBOC is due to a mutation in the 2 most common breast cancer genes - BRCA1 and BRCA2....
Myriad Will Seek Japanese Regulatory Approval for BRACAnalysis CDx®
Edit Stockhouse 07 Nov 2016
BRACAnalysis CDx is an in vitro diagnostic device intended for the qualitative detection and classification of variants in the protein coding regions and intron/exon boundaries of the BRCA1 and BRCA2 genes using genomic DNA obtained from whole blood specimens. It is approved for use as a companion diagnostic with AstraZeneca’s Lynparza (olaparib) for patients with advanced ovarian cancer in the United States and Europe ... ....
Myriad Will Seek Japanese Regulatory Approval for BRACAnalysis CDx® (Myriad Genetics Inc)
Edit Public Technologies 07 Nov 2016
(Source. Myriad Genetics Inc). SALT LAKE CITY, Nov. 07, 2016 (GLOBE NEWSWIRE) -- Myriad Genetics, Inc ... Capone, president and CEO, Myriad Genetics ... In December 2014, the U.S ... BRACAnalysis CDx is an in vitro diagnostic device intended for the qualitative detection and classification of variants in the protein coding regions and intron/exon boundaries of the BRCA1 and BRCA2 genes using genomic DNA obtained from whole blood specimens ... (noodl....
Scientists identify gene mutation that ups risk of breast cancer in men
Edit The Hindu 30 Oct 2016
.Researchers of the Anthropological Survey of India (AnSI) and the University of Calcutta, Department of Anthropology, have found that changes in a particular gene, called the BRCA2 gene, can increase the risk of breast cancer in men. A two-year study, which ended earlier this year, identified certain ‘novel mutations’ in the BRCA2 gene (BRCA refers to breast cancer), which makes men more susceptible to the disease....
Myriad’s BRACAnalysis CDx® Test Identifies Patients with Ovarian Cancer Who Would Benefit from Second-Line Maintenance ...
Edit Stockhouse 26 Oct 2016
BRACAnalysis CDx is an in vitro diagnostic device intended for the qualitative detection and classification of variants in the protein coding regions and intron/exon boundaries of the BRCA1 and BRCA2 genes using genomic DNA obtained from whole blood specimens collected in EDTA. Single nucleotide variants and small insertions and deletions ......
Myriad's BRACAnalysis CDx® Test Identifies Patients with Ovarian Cancer Who Would Benefit from Second-Line Maintenance Treatment with Olaparib (Myriad Genetics Inc)
Edit Public Technologies 26 Oct 2016
(Source. Myriad Genetics Inc). SALT LAKE CITY, Oct ... About BRACAnalysis CDxBRACAnalysis CDx is an in vitro diagnostic device intended for the qualitative detection and classification of variants in the protein coding regions and intron/exon boundaries of the BRCA1 and BRCA2 genes using genomic DNA obtained from whole blood specimens collected in EDTA ... Large deletions and duplications in BRCA1 and BRCA2 are detected using multiplex PCR....
26 October 2016 Lynparza Phase III SOLO-2 trial shows significant progression-free survival benefit Corporate Press Release (AstraZeneca plc)
Edit Public Technologies 26 Oct 2016
(Source. AstraZeneca plc) ... previous studies. 26 October 2016 ... NOTES TO EDITORS ... The trial, conducted in collaboration with the European Network for Gynaecological Oncological Trial Groups (ENGOT) and Groupe d'Investigateurs National pour l'Etude des Cancers de l'Ovaire et du sein (GINECO), randomised 295 patients with documented germline BRCA1 or BRCA2 mutations who had received at least 2 prior lines of platinum-based chemotherapy....
Positive results in AstraZeneca Lynparza trial
Edit Nasdaq Globe Newswire 26 Oct 2016
... conducted in collaboration with the European Network for Gynaecological Oncological Trial Groups (ENGOT) and Groupe d'Investigateurs National pour l'Etude des Cancers de l'Ovaire et du sein (GINECO), randomised 295 patients with documented germline BRCA1 or BRCA2 mutations who had received at least 2 prior lines of platinum-based chemotherapy....
TRICARE to expand preventive service coverage (USAF - United States Air Force)
Edit Public Technologies 21 Oct 2016
(Source. USAF - United States Air Force) FALLS CHURCH, Va. (AFNS) -- ... The new covered services include free genetic counseling by a TRICARE-authorized provider before BRCA1 or BRCA2 gene testing for women who are identified as high risk for breast cancer by their primary care providers, as well as the BRCA1 or BRCA2 gene testing for women who meet coverage guidelines under the existing laboratory developed test demonstration project....
Inspirational Belfast exhibition celebrates resilience of people living with cancer
Edit Belfast Telegraph 21 Oct 2016
The beauty and resilience of Northern Ireland men, women and children who have battled cancer are being celebrated in an inspiring photography exhibition in Belfast ... Share Go To ... "I thought she was incredibly beautiful and courageous and put up a post saying that I wished I had the courage to do this," she said ... Maura carries the BRCA2 gene and has a higher risk of developing breast cancer and ovarian cancer ... Belfast Telegraph....
Men Get Breast Cancer Too (GE Healthcare USA Holding Inc)
Edit Public Technologies 21 Oct 2016
(Source. GE Healthcare USA Holding Inc). Breast cancer doesn't just affect women-men can get it too, and many men don't know that. There is a lack of professional awareness and support due to uninformed care providers ... Everything at a diagnostic facility is geared towards women ... Everything is pink ... 'For example, the BRCA2 gene mutation is associated with an increased risk of breast cancer of about 6 in 100 (versus 1 in 1000 normally)....
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