- published: 26 Nov 2012
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A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a polypeptide or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains. Genes hold the information to build and maintain an organism's cells and pass genetic traits to offspring, although some organelles (e.g. mitochondria) are self-replicating and are not coded for by the organism's DNA. All organisms have many genes corresponding to various biological traits, some of which are immediately visible, such as eye color or number of limbs, and some of which are not, such as blood type or increased risk for specific diseases, or the thousands of basic biochemical processes that comprise life.
A modern working definition of a gene is "a locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions, and or other functional sequence regions ". Colloquial usage of the term gene (e.g. "good genes", "hair color gene") may actually refer to an allele: a gene is the basic instruction—a sequence of nucleic acids (DNA or, in the case of certain viruses RNA), while an allele is one variant of that gene. Referring to having a gene for a trait is no longer the scientifically accepted usage. In most cases, all people would have a gene for the trait in question, but certain people will have a specific allele of that gene, which results in the trait variant. Further, genes code for proteins, which might result in identifiable traits, but it is the gene, not the trait, which is inherited.
Steven Tyler (born Steven Victor Tallaricco; March 26, 1948) is an American singer, songwriter, and multi-instrumentalist, best known as the frontman and lead singer of the Boston-based rock band Aerosmith, in which he also plays the harmonica, and occasional piano and percussion. He is known as the "Demon of Screamin'" due to his high screams and his wide vocal range. He is also known for his on-stage acrobatics. During his high-energy performances, he usually dresses in bright, colorful outfits with his trademark scarves hanging from his microphone stand. In the 1970s, Tyler rose to prominence as the frontman of Aerosmith, which released such milestone hard rock albums as Toys in the Attic and Rocks. In the late 1970s and early 1980s, Tyler had a heavy drug and alcohol addiction, and the band's popularity waned.
He completed drug rehabilitation in 1986 and subsequently maintained sobriety for years, but had a relapse with prescription painkillers in the late 2000s, for which he successfully received treatment in 2009. After Aerosmith launched a remarkable comeback in the late 1980s and early 1990s with the albums Permanent Vacation, Pump, and Get a Grip, Tyler became a household name and has remained a relevant rock icon. As a result, he has since embarked on several solo endeavors including guest appearances on other artists' music, film and TV roles (including as a judge on American Idol), authoring a bestselling book, and solo work (including a Top 40 hit single in 2011). However, he has continued to record music and perform with Aerosmith, after more than 41 years in the band. He is included among Rolling Stone's 100 Greatest Singers. He was also ranked 3rd on Hit Parader's Top 100 Metal Vocalists of All Time. In 2001 he was inducted into the Rock and Roll Hall of Fame with Aerosmith, and he was the presenter when AC/DC was inducted into the Hall of Fame in 2003.
James Daniel May (born 16 January 1963) is an English television presenter, journalist and writer. He is best known for his role as co-presenter of the award-winning motoring program Top Gear alongside Jeremy Clarkson , and Richard Hammond.
On Top Gear, May has the nickname "Captain Slow" for his careful driving style, a love of small underpowered cars and habit of getting lost and distracted while driving. However, in a July 2010 episode of Top Gear he drove a Bugatti Veyron Super Sport, reaching a speed of 417.6 kilometres per hour (259.5 mph). After his attempt the Bugatti test driver Pierre-Henri Raphanel took the car to 430 kilometers per hour (267.5 mph).
May has presented a variety of other programs on themes including science and technology, toys, cars, wine culture, and the plight of manliness in modern times. In addition he has released a variety of DVDs and books with similar themes, and wrote a weekly column for The Daily Telegraph's motoring section.
James May was born in Bristol, one of four children; he has two sisters and a brother. May attended Caerleon Endowed Junior School in Newport, then in Monmouthshire. He spent his teenage years in South Yorkshire where he attended Oakwood Comprehensive School in Rotherham and was a choirboy at Whiston Parish Church. He was also at school with Life On Mars and Ashes to Ashes star Dean Andrews. A keen flautist and pianist, he later studied music at Pendle College, Lancaster University. After graduating, May briefly worked at a hospital in Chelsea as a records officer, and had a short stint in Her Majesty's Civil Service.
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