Aguirre is a surname of Basque origin (currently spelled in Basque language, according to current ortography, as Agirre) as well as a place name arguably meaning 'prominence' in old Basque and may refer to:
Aguirre is a surname of Basque origin. Lope de Aguirre was one of the first Europeans to explore the 'New World'. In the United States, 42,483 people bear the surname Aguirre (statistically the country's 831st most common surname)