Eric Patrick Clapton, CBE, (born 30 March 1945) is an English guitarist and singer-songwriter. Clapton is the only three-time inductee to the Rock and Roll Hall of Fame: once as a solo artist, and separately as a member of The Yardbirds and Cream. Clapton has been referred to as one of the most important and influential guitarists of all time. Clapton ranked second in Rolling Stone magazine's list of the "100 Greatest Guitarists of All Time" and fourth in Gibson's Top 50 Guitarists of All Time.

In the mid 1960s, Clapton departed from the Yardbirds to play blues with John Mayall & the Bluesbreakers. In his one-year stay with Mayall, Clapton gained the nickname "Slowhand". Immediately after leaving Mayall, Clapton formed Cream, a power trio with drummer Ginger Baker and bassist Jack Bruce in which Clapton played sustained blues improvisations and "arty, blues-based psychedelic pop." For most of the 1970s, Clapton's output bore the influence of the mellow style of J.J. Cale and the reggae of Bob Marley. His version of Marley's "I Shot the Sheriff" helped reggae reach a mass market. Two of his most popular recordings were "Layla", recorded by Derek and the Dominos, another band he formed and Robert Johnson's "Crossroads", recorded by Cream. A recipient of seventeen Grammy Awards, in 2004 Clapton was awarded a CBE for services to music. In 1998, Clapton, a recovering alcoholic and drug addict, founded the Crossroads Centre on Antigua, a medical facility for recovering substance abusers.

George "Buddy" Guy (born July 30, 1936) is an American blues guitarist and singer. Critically acclaimed, he is a pioneer of the Chicago blues sound and has served as an influence to some of the most notable musicians of his generation. "A key influence on Eric Clapton, Jimi Hendrix and Stevie Ray Vaughan, Buddy Guy put the Louisiana hurricane in 1960s electric Chicago blues as a member of Muddy Waters' band and as a house guitarist at Chess Records. A native of the Baton Rouge area, he combined a blazing modernism with a fierce grip on his roots, playing frantic leads heavy with swampy funk on Howlin' Wolf's 'Killing Floor' and Koko Taylor's 'Wang Dang Doodle' as well as on his own Chess sides and the fine series of records he made with harp man Junior Wells. One of the last active connections to the golden age of Chess, Guy still plays with his original fire."

Ranked thirtieth in Rolling Stone magazine's list of the "100 Greatest Guitarists of All Time", Guy is known for his showmanship on stage: playing his guitar with drumsticks or strolling into the audience while playing solos. His song "Stone Crazy" was ranked seventy-eighth in list of the 100 Greatest Guitar Songs of All Time also of Rolling Stone.

John Clayton Mayer ( /ˈmeɪ.ər/ MAY-ər; (born October 16, 1977) is an American pop and blues rock musician, singer-songwriter, recording artist, and music producer. Born in Bridgeport, Connecticut and raised in Fairfield, Connecticut, he attended Berklee College of Music in Boston. He moved to Atlanta in 1997, where he refined his skills and gained a following, and he now lives in New York City. His first two studio albums, Room for Squares and Heavier Things, did well commercially, achieving multi-platinum status. In 2003, he won a Grammy Award for Best Male Pop Vocal Performance for "Your Body Is a Wonderland."

Mayer began his career performing mainly acoustic rock, but gradually began a transition towards the blues genre in 2005 by collaborating with renowned blues artists such as B. B. King, Buddy Guy, and Eric Clapton, and by forming the John Mayer Trio. The blues influence can be heard throughout his 2005 live album Try! with the John Mayer Trio and his third studio album Continuum, released in September 2006. At the 49th Annual Grammy Awards in 2007 Mayer won Best Pop Vocal Album for Continuum and Best Male Pop Vocal Performance for "Waiting on the World to Change". He released his fourth studio album, Battle Studies, in November 2009. His fifth album, Born and Raised, was released on May 22, 2012. He has sold over 10 million albums in the U.S. and 20 million albums worldwide.