O'odham (pronounced [ˈɔʔɔd̪ɦam]) is an Uto-Aztecan language of southern Arizona and northern Sonora where the Tohono O'odham (formerly called the Papago) and Pima reside. As of the year 2000, there were estimated to be approximately 9,750 speakers in the United States and Mexico combined, although there may be more due to underreporting.

It is the 10th most-spoken indigenous language in the United States, the 3rd most-spoken indigenous language in Arizona after Apache and Navajo. It is the 3rd most-spoken language in Pinal County and the 4th most-spoken language in Pima County.

Approximately 8% of O'odham speakers in the US speak English "not well" or "not at all", according to results of the 2000 Census. Approximately 13% of O'odham speakers in the US were between the ages of 5 and 17, and among the younger O'odham speakers, approximately 4% were reported as speaking English "not well" or "not at all".

Native names for the language, depending on the dialect and orthography, include Oʼodham ha-ñeʼokĭ, Oʼottham ha-neoki, and Oʼodham ñiok.

The O'odham peoples, including the Tohono O'odham or Papago, the Pima or Akimel O'odham, and the Hia C-ed O'odham, are an indigenous Uto-Aztecan peoples of the Sonoran desert in southern and central Arizona and northern Sonora, united by a common heritage language, the O'odham language. Today, many O'odham live in the Tohono O'odham Nation, the San Xavier Indian Reservation, the Gila River Indian Community, the Salt River Pima-Maricopa Indian Community, the Ak-Chin Indian Community or off-reservation in one of the cities or towns of Arizona.

Coordinates: 50°47′N 4°10′W / 50.79°N 4.17°W / 50.79; -04.17

Odham is a village in Devon, England.