Catherine Anne O'Hara (born March 4, 1954) is a Canadian-American actress, writer and comedienne. She is well known for her comedy work on SCTV, and her roles in the films After Hours, Beetlejuice, Home Alone, and The Nightmare Before Christmas, and also in the mockumentary films written and directed by Christopher Guest including Waiting for Guffman, Best in Show, A Mighty Wind, and For Your Consideration.
O'Hara was born in Toronto, Ontario, into a large Irish Catholic family, and was raised Roman Catholic. She attended Burnhamthorpe Collegiate Institute, where she first met Robin Duke, who went on to her own comedy career.
Catherine started her comedy career in 1974 as a cast member of The Second City in her native Toronto. She was an understudy for Gilda Radner until Radner left for Saturday Night Live. Two years later, this theatre troupe created the sketch comedy show SCTV, for which O'Hara became a regular performer. Her memorable characterizations on the show included Las Vegas scorcher Lola Heatherton, buzzer-happy game show contestant Margaret Meehan, raunchy nightclub comedian Dusty Towne, soap opera seductress Sue Ellen, and stage actress Sue Bopper Simpson.